TY - JOUR
T1 - Increased Volume Reduction of Late Left-Atrial Emptying for Patients with Pseudonormal Mitral Inflow
T2 - An Analysis for Differentiation between Normal and Pseudonormal Mitral Inflow
AU - Hung, Ming Jui
AU - Cherng, Wen Jin
AU - Cheng, Chi Wen
PY - 2003/11
Y1 - 2003/11
N2 - This study was designed to define the role of left atrial (LA) wall motion during left ventricular (LV) diastolic phase for patients with pseudonormal mitral inflow. We perform the M-mode of posterior aortic, indicating LA, wall motion, and Doppler echocardiography following cardiac catheterization among 71 patients with a ratio of early (E) to late mitral flow (A) > 1. The amplitude of total LA wall motion (TM), early LA rapid emptying (EM), and late LA emptying (AM) during the LV diastolic phase were all derived from M-mode analysis. Study patients were classified into two distinct groups according to the LV end-diastolic pressure (EDP):patients with a LVEDP value < 15 mmHg (n = 36, normal group), and patients with a LVEDP value ≥ 15 mmHg (n = 35, pseudonormal group). Values of AM (4.7 ± 1.2 vs 5.5 ± 1.2 mm) and A M/TM (0.43 ± 0.07 vs 0.55 ± 0.08) for the normal and pseudonormal groups, respectively, were significantly higher for the pseudonormal group, whereas EM (6.6 ± 1.8 vs 4.8 ± 1.4 mm), TM (11 ± 3 vs 10 ± 2 mm), EM/A M (1.41 ± 0.46 vs 0.91 ± 0.28), EM/T M (0.58 ± 0.10 vs 0.48 ± 0.07) were significantly higher for the normal group. Among these parameters, AM/T M correlated best with the time constant of LV isovolumic relaxation (r = 0.77, P < 0.001). Using an AM/TM ratio value of >0.5 as an indicator of LV diastolic function abnormality, the sensitivity, specificity, positive predictive values, and negative predictive values for the detection of pseudonormalization were 85%, 94%, 94%, and 87%, respectively. These findings suggest that the increased volume reduction of late LA emptying (AM/TM) during LV diastolic phase assessed by M-mode echocardiography is useful for evaluating pseudonormal mitral inflow.
AB - This study was designed to define the role of left atrial (LA) wall motion during left ventricular (LV) diastolic phase for patients with pseudonormal mitral inflow. We perform the M-mode of posterior aortic, indicating LA, wall motion, and Doppler echocardiography following cardiac catheterization among 71 patients with a ratio of early (E) to late mitral flow (A) > 1. The amplitude of total LA wall motion (TM), early LA rapid emptying (EM), and late LA emptying (AM) during the LV diastolic phase were all derived from M-mode analysis. Study patients were classified into two distinct groups according to the LV end-diastolic pressure (EDP):patients with a LVEDP value < 15 mmHg (n = 36, normal group), and patients with a LVEDP value ≥ 15 mmHg (n = 35, pseudonormal group). Values of AM (4.7 ± 1.2 vs 5.5 ± 1.2 mm) and A M/TM (0.43 ± 0.07 vs 0.55 ± 0.08) for the normal and pseudonormal groups, respectively, were significantly higher for the pseudonormal group, whereas EM (6.6 ± 1.8 vs 4.8 ± 1.4 mm), TM (11 ± 3 vs 10 ± 2 mm), EM/A M (1.41 ± 0.46 vs 0.91 ± 0.28), EM/T M (0.58 ± 0.10 vs 0.48 ± 0.07) were significantly higher for the normal group. Among these parameters, AM/T M correlated best with the time constant of LV isovolumic relaxation (r = 0.77, P < 0.001). Using an AM/TM ratio value of >0.5 as an indicator of LV diastolic function abnormality, the sensitivity, specificity, positive predictive values, and negative predictive values for the detection of pseudonormalization were 85%, 94%, 94%, and 87%, respectively. These findings suggest that the increased volume reduction of late LA emptying (AM/TM) during LV diastolic phase assessed by M-mode echocardiography is useful for evaluating pseudonormal mitral inflow.
KW - Atrium
KW - Diastole
KW - Echocardiography
KW - Ventricles
UR - http://www.scopus.com/inward/record.url?scp=0344686253&partnerID=8YFLogxK
U2 - 10.1111/j.0742-2822.2003.03007.x
DO - 10.1111/j.0742-2822.2003.03007.x
M3 - 文章
C2 - 14641374
AN - SCOPUS:0344686253
SN - 0742-2822
VL - 20
SP - 703
EP - 709
JO - Echocardiography
JF - Echocardiography
IS - 8
ER -