Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

Cheng Hsun Chiu; Lin Hui Su; Yhu Chering Huang; Jui Chia Lai; Hsiu Ling Chen; Tsu Lan Wu; Tzou Yien Lin

doi:10.1128/AAC.01563-06

Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

Cheng Hsun Chiu^*
, Lin Hui Su
, Yhu Chering Huang
, Jui Chia Lai
, Hsiu Ling Chen
, Tsu Lan Wu
, Tzou Yien Lin

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

29 Scopus citations

Abstract

The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

Original language	English
Pages (from-to)	3404-3406
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	51
Issue number	9
DOIs	https://doi.org/10.1128/AAC.01563-06
State	Published - 09 2007

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10.1128/AAC.01563-06

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@article{002d43b1fa1448958428ba1c5e64840a,

title = "Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan",

abstract = "The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90\% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.",

author = "Chiu, \{Cheng Hsun\} and Su, \{Lin Hui\} and Huang, \{Yhu Chering\} and Lai, \{Jui Chia\} and Chen, \{Hsiu Ling\} and Wu, \{Tsu Lan\} and Lin, \{Tzou Yien\}",

year = "2007",

month = sep,

doi = "10.1128/AAC.01563-06",

language = "英语",

volume = "51",

pages = "3404--3406",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "9",

}

Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan. / Chiu, Cheng Hsun; Su, Lin Hui; Huang, Yhu Chering et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 51, No. 9, 09.2007, p. 3404-3406.

Research output: Contribution to journal › Journal Article › peer-review

TY - JOUR

T1 - Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

AU - Chiu, Cheng Hsun

AU - Su, Lin Hui

AU - Huang, Yhu Chering

AU - Lai, Jui Chia

AU - Chen, Hsiu Ling

AU - Wu, Tsu Lan

AU - Lin, Tzou Yien

PY - 2007/9

Y1 - 2007/9

N2 - The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

AB - The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

UR - https://www.scopus.com/pages/publications/35948975073

U2 - 10.1128/AAC.01563-06

DO - 10.1128/AAC.01563-06

M3 - 文章

C2 - 17591850

AN - SCOPUS:35948975073

SN - 0066-4804

VL - 51

SP - 3404

EP - 3406

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 9

ER -

Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

Abstract

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