Influence of relative age on diagnosis and treatment of attention-deficit hyperactivity disorder in taiwanese children

Mu Hong Chen; Wen Hsuan Lan; Ya Mei Bai; Kai Lin Huang; Tung Ping Su; Shih Jen Tsai; Cheng Ta Li; Wei Chen Lin; Wen Han Chang; Tai Long Pan; Tzeng Ji Chen; Ju Wei Hsu

doi:10.1016/j.jpeds.2016.02.012

Influence of relative age on diagnosis and treatment of attention-deficit hyperactivity disorder in taiwanese children

Mu Hong Chen^*, Wen Hsuan Lan, Ya Mei Bai, Kai Lin Huang, Tung Ping Su, Shih Jen Tsai, Cheng Ta Li, Wei Chen Lin, Wen Han Chang, Tai Long Pan, Tzeng Ji Chen, Ju Wei Hsu

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

40 Scopus citations

Abstract

Objective To determine the potential influence of relative age on the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD), especially in reference to an Asian country. Study design A total of 378 881 subjects aged 4-17 years during the study period (September 1, 1997 to August 31, 2011) were enrolled in our study from the Taiwan National Health Insurance Research Database. Logistic regression analysis was used to examine the likelihood of receiving ADHD diagnosis and treatment for those who were born in August (the youngest) compared with those who were born in September (the oldest). Results Both boys and girls born in August had a higher risk of being diagnosed with ADHD (OR 1.63, 95% CI 1.45-1.84; OR 1.71, 95% CI 1.36-2.15) and receiving ADHD medication (OR 1.76, 95% CI 1.53-2.02; OR 1.65, 95% CI 1.26-2.18) than those born in September. Sensitivity tests conducted over different periods revealed consistent findings. Conclusions Relative age, as an indicator of neurocognitive maturity, is crucial in the risk of being diagnosed with ADHD and receiving ADHD medication among children and adolescents. Our findings emphasize the importance of considering the age of a child within a grade when diagnosing ADHD and prescribing medication for treating ADHD.

Original language	English
Pages (from-to)	162-167.e1
Journal	Journal of Pediatrics
Volume	172
DOIs	https://doi.org/10.1016/j.jpeds.2016.02.012
State	Published - 01 05 2016

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© 2016 Elsevier Inc.

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title = "Influence of relative age on diagnosis and treatment of attention-deficit hyperactivity disorder in taiwanese children",

abstract = "Objective To determine the potential influence of relative age on the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD), especially in reference to an Asian country. Study design A total of 378 881 subjects aged 4-17 years during the study period (September 1, 1997 to August 31, 2011) were enrolled in our study from the Taiwan National Health Insurance Research Database. Logistic regression analysis was used to examine the likelihood of receiving ADHD diagnosis and treatment for those who were born in August (the youngest) compared with those who were born in September (the oldest). Results Both boys and girls born in August had a higher risk of being diagnosed with ADHD (OR 1.63, 95% CI 1.45-1.84; OR 1.71, 95% CI 1.36-2.15) and receiving ADHD medication (OR 1.76, 95% CI 1.53-2.02; OR 1.65, 95% CI 1.26-2.18) than those born in September. Sensitivity tests conducted over different periods revealed consistent findings. Conclusions Relative age, as an indicator of neurocognitive maturity, is crucial in the risk of being diagnosed with ADHD and receiving ADHD medication among children and adolescents. Our findings emphasize the importance of considering the age of a child within a grade when diagnosing ADHD and prescribing medication for treating ADHD.",

author = "Chen, {Mu Hong} and Lan, {Wen Hsuan} and Bai, {Ya Mei} and Huang, {Kai Lin} and Su, {Tung Ping} and Tsai, {Shih Jen} and Li, {Cheng Ta} and Lin, {Wei Chen} and Chang, {Wen Han} and Pan, {Tai Long} and Chen, {Tzeng Ji} and Hsu, {Ju Wei}",

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year = "2016",

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day = "1",

doi = "10.1016/j.jpeds.2016.02.012",

language = "英语",

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T1 - Influence of relative age on diagnosis and treatment of attention-deficit hyperactivity disorder in taiwanese children

AU - Chen, Mu Hong

AU - Lan, Wen Hsuan

AU - Bai, Ya Mei

AU - Huang, Kai Lin

AU - Su, Tung Ping

AU - Tsai, Shih Jen

AU - Li, Cheng Ta

AU - Lin, Wei Chen

AU - Chang, Wen Han

AU - Pan, Tai Long

AU - Chen, Tzeng Ji

AU - Hsu, Ju Wei

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Objective To determine the potential influence of relative age on the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD), especially in reference to an Asian country. Study design A total of 378 881 subjects aged 4-17 years during the study period (September 1, 1997 to August 31, 2011) were enrolled in our study from the Taiwan National Health Insurance Research Database. Logistic regression analysis was used to examine the likelihood of receiving ADHD diagnosis and treatment for those who were born in August (the youngest) compared with those who were born in September (the oldest). Results Both boys and girls born in August had a higher risk of being diagnosed with ADHD (OR 1.63, 95% CI 1.45-1.84; OR 1.71, 95% CI 1.36-2.15) and receiving ADHD medication (OR 1.76, 95% CI 1.53-2.02; OR 1.65, 95% CI 1.26-2.18) than those born in September. Sensitivity tests conducted over different periods revealed consistent findings. Conclusions Relative age, as an indicator of neurocognitive maturity, is crucial in the risk of being diagnosed with ADHD and receiving ADHD medication among children and adolescents. Our findings emphasize the importance of considering the age of a child within a grade when diagnosing ADHD and prescribing medication for treating ADHD.

AB - Objective To determine the potential influence of relative age on the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD), especially in reference to an Asian country. Study design A total of 378 881 subjects aged 4-17 years during the study period (September 1, 1997 to August 31, 2011) were enrolled in our study from the Taiwan National Health Insurance Research Database. Logistic regression analysis was used to examine the likelihood of receiving ADHD diagnosis and treatment for those who were born in August (the youngest) compared with those who were born in September (the oldest). Results Both boys and girls born in August had a higher risk of being diagnosed with ADHD (OR 1.63, 95% CI 1.45-1.84; OR 1.71, 95% CI 1.36-2.15) and receiving ADHD medication (OR 1.76, 95% CI 1.53-2.02; OR 1.65, 95% CI 1.26-2.18) than those born in September. Sensitivity tests conducted over different periods revealed consistent findings. Conclusions Relative age, as an indicator of neurocognitive maturity, is crucial in the risk of being diagnosed with ADHD and receiving ADHD medication among children and adolescents. Our findings emphasize the importance of considering the age of a child within a grade when diagnosing ADHD and prescribing medication for treating ADHD.

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ER -

Influence of relative age on diagnosis and treatment of attention-deficit hyperactivity disorder in taiwanese children

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