Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

Chien Chih Chen*, Hon Yi Chen, Ming Shi Shiao, Yun Lian Lin, Yueh Hsiung Kuo, Jun Chih Ou

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

54 Scopus citations

Abstract

Based on the inhibition of Cu2+-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and largesin, which do not contain phenol groups, were found much less active.

Original languageEnglish
Pages (from-to)709-711
Number of pages3
JournalPlanta Medica
Volume65
Issue number8
DOIs
StatePublished - 12 1999
Externally publishedYes

Keywords

  • Antioxidants
  • Forsythia suspensa (Thunb.) Vahl.
  • Magnolia coco (Lour.) DC.
  • Magnoliaceae
  • Oleaceae
  • Phillygenin
  • Pinoresinol
  • Syringaresinol

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