Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

Chien Chih Chen; Hon Yi Chen; Ming Shi Shiao; Yun Lian Lin; Yueh Hsiung Kuo; Jun Chih Ou

doi:10.1055/s-1999-14093

Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

Chien Chih Chen^*, Hon Yi Chen, Ming Shi Shiao, Yun Lian Lin, Yueh Hsiung Kuo, Jun Chih Ou

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

58 Scopus citations

Abstract

Based on the inhibition of Cu²⁺-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and largesin, which do not contain phenol groups, were found much less active.

Original language	English
Pages (from-to)	709-711
Number of pages	3
Journal	Planta Medica
Volume	65
Issue number	8
DOIs	https://doi.org/10.1055/s-1999-14093
State	Published - 12 1999
Externally published	Yes

Keywords

Antioxidants
Forsythia suspensa (Thunb.) Vahl.
Magnolia coco (Lour.) DC.
Magnoliaceae
Oleaceae
Phillygenin
Pinoresinol
Syringaresinol

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title = "Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco",

abstract = "Based on the inhibition of Cu2+-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and largesin, which do not contain phenol groups, were found much less active.",

keywords = "Antioxidants, Forsythia suspensa (Thunb.) Vahl., Magnolia coco (Lour.) DC., Magnoliaceae, Oleaceae, Phillygenin, Pinoresinol, Syringaresinol",

author = "Chen, {Chien Chih} and Chen, {Hon Yi} and Shiao, {Ming Shi} and Lin, {Yun Lian} and Kuo, {Yueh Hsiung} and Ou, {Jun Chih}",

year = "1999",

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doi = "10.1055/s-1999-14093",

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volume = "65",

pages = "709--711",

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T1 - Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

AU - Chen, Chien Chih

AU - Chen, Hon Yi

AU - Shiao, Ming Shi

AU - Lin, Yun Lian

AU - Kuo, Yueh Hsiung

AU - Ou, Jun Chih

PY - 1999/12

Y1 - 1999/12

N2 - Based on the inhibition of Cu2+-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and largesin, which do not contain phenol groups, were found much less active.

AB - Based on the inhibition of Cu2+-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and largesin, which do not contain phenol groups, were found much less active.

KW - Antioxidants

KW - Forsythia suspensa (Thunb.) Vahl.

KW - Magnolia coco (Lour.) DC.

KW - Magnoliaceae

KW - Oleaceae

KW - Phillygenin

KW - Pinoresinol

KW - Syringaresinol

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DO - 10.1055/s-1999-14093

M3 - 文章

C2 - 10630110

AN - SCOPUS:0032734548

SN - 0032-0943

VL - 65

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EP - 711

JO - Planta Medica

JF - Planta Medica

IS - 8

ER -

Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco

Abstract

Keywords

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