Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results

Ching Yeh Hsiung*, Margie A. Hunt, Ellen D. Yorke, Chen Shou Chui, Jason Hu, Jian Ping Xiong, Clifton C. Ling, Sing Kai Lo, Chong Jong Wang, Eng Yen Huang, Howard I. Amols

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

11 Scopus citations

Abstract

The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalRadiotherapy and Oncology
Volume77
Issue number1
DOIs
StatePublished - 10 2005
Externally publishedYes

Keywords

  • Anatomic factor
  • Intensity-modulated radiotherapy
  • Inverse planning
  • Nasopharyngeal carcinoma
  • Optimization

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