Intra blood-cerebrospinal fluid-barrier detection of hepatitis B virus

Chia C. Pao*, Shaw Yun Wu, Iou Jih Hung, Kim Thean Ng, Yun Fan Liaw, Szecheng J. Lo

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations


Hepatitis B, a major public health concern worldwide, is caused by hepatitis type B virus, a hepdnavirus that infects only human and certain nonhuman primates, and replicates strictly in hepatocytes. By using the techniques of slot and Southern blot DNA hybridization, and electron microscopy, the presence of HBV was identified in the cerebrospinal fluid of three affected individuals.

Original languageEnglish
Pages (from-to)452-455
Number of pages4
JournalBiochemical and Biophysical Research Communications
Issue number2
StatePublished - 31 07 1987


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