Intraamniotic detection of Chlamydia trachomatis deoxyribonucleic acid sequences by polymerase chain reaction

Chia C. Pao*, Shu Min Kao, Han Chow Wang, Cagge C. Lee

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

31 Scopus citations

Abstract

The presence of Chlamydia trachomatis in cervicovaginal cells and amniotic fluid of pregnant women was examined by culture and by polymerase chain reaction deoxyribonucleic acid amplification methods. Chlamydial deoxyribonucleic acid sequences were found in nine of 31 (29.0%) cervicovaginal cell specimens, five of which also were positive by culture method. Amniotic fluid specimens from two of the nine (22.2%) cervicovaginal chlamydial deoxyribonucleic acid-positive women and none from the remaining 22 cervicovaginal chlamydial deoxyribonucleic acid-negative women were found to contain chlamydial deoxyribonucleic acid. The results underscore the significance and frequency of intraamniotic chlamydial infection in women with urogenital chlamydial infections.

Original languageEnglish
Pages (from-to)1295-1299
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume164
Issue number5 PART 1
DOIs
StatePublished - 05 1991

Keywords

  • Chlamydia trachomatis
  • intraamniotic infection
  • polymerase chain reaction

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