Investigation of disruption of cell colony formation process by alternating electric field

Chun Hao Huang, Kin Fong Lei*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In vitro 3D cell culture device embedded with stimulating electrodes was developed for the investigation of disruption of cell colony formation process. Cells encapsulated in soft hydrogel were cultured and proliferated to cell colonies in the device. Alternating electric field was then applied to investigate the response of cell colonies. Results showed that the electric field at frequency of 130 kHz and potential of 0.5 Vp-p was the most effective conditions to inhibit the growth of cancer cell colonies.

Original languageEnglish
Title of host publicationTRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1656-1659
Number of pages4
ISBN (Electronic)9781538627310
DOIs
StatePublished - 26 07 2017
Event19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 - Kaohsiung, Taiwan
Duration: 18 06 201722 06 2017

Publication series

NameTRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

Conference19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
Country/TerritoryTaiwan
CityKaohsiung
Period18/06/1722/06/17

Bibliographical note

Publisher Copyright:
© 2017 IEEE.

Keywords

  • Cancer
  • Cell colony
  • Electrical stimulation
  • Proliferation inhibition

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