Investigation of disruption of cell colony formation process by alternating electric field

Chun Hao Huang; Kin Fong Lei

doi:10.1109/TRANSDUCERS.2017.7994382

Investigation of disruption of cell colony formation process by alternating electric field

Chun Hao Huang
, Kin Fong Lei^*

^*Corresponding author for this work

Master Program in Nano-Electronic Engineering and Design

Chang Gung University
Chang Gung Memorial Hospital

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

In vitro 3D cell culture device embedded with stimulating electrodes was developed for the investigation of disruption of cell colony formation process. Cells encapsulated in soft hydrogel were cultured and proliferated to cell colonies in the device. Alternating electric field was then applied to investigate the response of cell colonies. Results showed that the electric field at frequency of 130 kHz and potential of 0.5 V_p-p was the most effective conditions to inhibit the growth of cancer cell colonies.

Original language	English
Title of host publication	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1656-1659
Number of pages	4
ISBN (Electronic)	9781538627310
DOIs	https://doi.org/10.1109/TRANSDUCERS.2017.7994382
State	Published - 26 07 2017
Event	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 - Kaohsiung, Taiwan Duration: 18 06 2017 → 22 06 2017

Publication series

Name	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

Conference	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
Country/Territory	Taiwan
City	Kaohsiung
Period	18/06/17 → 22/06/17

Bibliographical note

Publisher Copyright:
© 2017 IEEE.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer
Cell colony
Electrical stimulation
Proliferation inhibition

Access to Document

10.1109/TRANSDUCERS.2017.7994382

Cite this

Huang, C. H., & Lei, K. F. (2017). Investigation of disruption of cell colony formation process by alternating electric field. In TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 1656-1659). Article 7994382 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2017.7994382

Huang, Chun Hao ; Lei, Kin Fong. / Investigation of disruption of cell colony formation process by alternating electric field. TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1656-1659 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

@inproceedings{5e5e9cfffebc486c9f9f2bd4be0a747e,

title = "Investigation of disruption of cell colony formation process by alternating electric field",

abstract = "In vitro 3D cell culture device embedded with stimulating electrodes was developed for the investigation of disruption of cell colony formation process. Cells encapsulated in soft hydrogel were cultured and proliferated to cell colonies in the device. Alternating electric field was then applied to investigate the response of cell colonies. Results showed that the electric field at frequency of 130 kHz and potential of 0.5 Vp-p was the most effective conditions to inhibit the growth of cancer cell colonies.",

keywords = "Cancer, Cell colony, Electrical stimulation, Proliferation inhibition",

author = "Huang, \{Chun Hao\} and Lei, \{Kin Fong\}",

note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 ; Conference date: 18-06-2017 Through 22-06-2017",

year = "2017",

month = jul,

day = "26",

doi = "10.1109/TRANSDUCERS.2017.7994382",

language = "英语",

series = "TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "1656--1659",

booktitle = "TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems",

address = "美国",

}

Huang, CH & Lei, KF 2017, Investigation of disruption of cell colony formation process by alternating electric field. in TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems., 7994382, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, Institute of Electrical and Electronics Engineers Inc., pp. 1656-1659, 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017, Kaohsiung, Taiwan, 18/06/17. https://doi.org/10.1109/TRANSDUCERS.2017.7994382

Investigation of disruption of cell colony formation process by alternating electric field. / Huang, Chun Hao; Lei, Kin Fong.
TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. p. 1656-1659 7994382 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Investigation of disruption of cell colony formation process by alternating electric field

AU - Huang, Chun Hao

AU - Lei, Kin Fong

PY - 2017/7/26

Y1 - 2017/7/26

N2 - In vitro 3D cell culture device embedded with stimulating electrodes was developed for the investigation of disruption of cell colony formation process. Cells encapsulated in soft hydrogel were cultured and proliferated to cell colonies in the device. Alternating electric field was then applied to investigate the response of cell colonies. Results showed that the electric field at frequency of 130 kHz and potential of 0.5 Vp-p was the most effective conditions to inhibit the growth of cancer cell colonies.

AB - In vitro 3D cell culture device embedded with stimulating electrodes was developed for the investigation of disruption of cell colony formation process. Cells encapsulated in soft hydrogel were cultured and proliferated to cell colonies in the device. Alternating electric field was then applied to investigate the response of cell colonies. Results showed that the electric field at frequency of 130 kHz and potential of 0.5 Vp-p was the most effective conditions to inhibit the growth of cancer cell colonies.

KW - Cancer

KW - Cell colony

KW - Electrical stimulation

KW - Proliferation inhibition

UR - https://www.scopus.com/pages/publications/85029363552

U2 - 10.1109/TRANSDUCERS.2017.7994382

DO - 10.1109/TRANSDUCERS.2017.7994382

M3 - 会议稿件

AN - SCOPUS:85029363552

T3 - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

SP - 1656

EP - 1659

BT - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017

Y2 - 18 June 2017 through 22 June 2017

ER -

Huang CH, Lei KF. Investigation of disruption of cell colony formation process by alternating electric field. In TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1656-1659. 7994382. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). doi: 10.1109/TRANSDUCERS.2017.7994382

Investigation of disruption of cell colony formation process by alternating electric field

Abstract

Publication series

Conference

Bibliographical note

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this