Kawasaki disease with G6PD deficiency-Report of one case and literature Review

Chia Hao Chen; Li Yan Lin; Kuender D. Yang; Kai Sheng Hsieh; Ho Chang Kuo

doi:10.1016/j.jmii.2012.05.002

Kawasaki disease with G6PD deficiency-Report of one case and literature Review

Chia Hao Chen, Li Yan Lin, Kuender D. Yang, Kai Sheng Hsieh, Ho Chang Kuo^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Journal Article › peer-review

6 Scopus citations

Abstract

Kawasaki disease (KD) is a systemic vasculitis primarily affecting children who are younger than 5 years. The most serious complications are coronary artery aneurysms and sequelae of vasculitis with the subsequent development of coronary artery aneurysm. According to the literature, intravenous immunoglobulin (IVIG) plus high-dose aspirin (acetylsalicylic acid) were standard treatment for KD, whereas low-dose aspirin (3-5 mg/kg/day) was used for thrombocytosis in KD via antiplatelet effect. However, aspirin has been reported to have hemolytic potential in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We report a child with G6PD-deficiency who has KD, and review the literature.

Original language	English
Pages (from-to)	261-263
Number of pages	3
Journal	Journal of Microbiology, Immunology and Infection
Volume	47
Issue number	3
DOIs	https://doi.org/10.1016/j.jmii.2012.05.002
State	Published - 06 2014

Keywords

Aspirin
G6PD deficiency
Kawasaki disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jmii.2012.05.002

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title = "Kawasaki disease with G6PD deficiency-Report of one case and literature Review",

abstract = "Kawasaki disease (KD) is a systemic vasculitis primarily affecting children who are younger than 5 years. The most serious complications are coronary artery aneurysms and sequelae of vasculitis with the subsequent development of coronary artery aneurysm. According to the literature, intravenous immunoglobulin (IVIG) plus high-dose aspirin (acetylsalicylic acid) were standard treatment for KD, whereas low-dose aspirin (3-5 mg/kg/day) was used for thrombocytosis in KD via antiplatelet effect. However, aspirin has been reported to have hemolytic potential in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We report a child with G6PD-deficiency who has KD, and review the literature.",

keywords = "Aspirin, G6PD deficiency, Kawasaki disease",

author = "Chen, {Chia Hao} and Lin, {Li Yan} and Yang, {Kuender D.} and Hsieh, {Kai Sheng} and Kuo, {Ho Chang}",

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AU - Chen, Chia Hao

AU - Lin, Li Yan

AU - Yang, Kuender D.

AU - Hsieh, Kai Sheng

AU - Kuo, Ho Chang

PY - 2014/6

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AB - Kawasaki disease (KD) is a systemic vasculitis primarily affecting children who are younger than 5 years. The most serious complications are coronary artery aneurysms and sequelae of vasculitis with the subsequent development of coronary artery aneurysm. According to the literature, intravenous immunoglobulin (IVIG) plus high-dose aspirin (acetylsalicylic acid) were standard treatment for KD, whereas low-dose aspirin (3-5 mg/kg/day) was used for thrombocytosis in KD via antiplatelet effect. However, aspirin has been reported to have hemolytic potential in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We report a child with G6PD-deficiency who has KD, and review the literature.

KW - Aspirin

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Kawasaki disease with G6PD deficiency-Report of one case and literature Review

Abstract

Keywords

UN SDGs

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