Kawasaki disease with G6PD deficiency-Report of one case and literature Review

Chia Hao Chen, Li Yan Lin, Kuender D. Yang, Kai Sheng Hsieh, Ho Chang Kuo*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations

Abstract

Kawasaki disease (KD) is a systemic vasculitis primarily affecting children who are younger than 5 years. The most serious complications are coronary artery aneurysms and sequelae of vasculitis with the subsequent development of coronary artery aneurysm. According to the literature, intravenous immunoglobulin (IVIG) plus high-dose aspirin (acetylsalicylic acid) were standard treatment for KD, whereas low-dose aspirin (3-5 mg/kg/day) was used for thrombocytosis in KD via antiplatelet effect. However, aspirin has been reported to have hemolytic potential in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We report a child with G6PD-deficiency who has KD, and review the literature.

Original languageEnglish
Pages (from-to)261-263
Number of pages3
JournalJournal of Microbiology, Immunology and Infection
Volume47
Issue number3
DOIs
StatePublished - 06 2014

Keywords

  • Aspirin
  • G6PD deficiency
  • Kawasaki disease

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