Klebsiella pneumoniae meningitis: Prognostic factors

Lok Ming Tang*, Sien Tsong Chen

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

28 Scopus citations

Abstract

All 42 cases of Klebsiella pneumoniae meningitis diagnosed between 1981 and 1991 were evaluated. These accounted for 13% of patients with blood and/or cerebrospinal fluid cultureproven bacterial meningitis. There was an increased incidence of K. pneumoniae meningitis from the first 6 years of study (7% to the last 5 years (16% K. pneumoniae became increasingly important not only in community-acquired meningitis but also in nosocomial meningitis. 12/13 nosocomial cases were patients who had undergone neurosurgical procedures. The overall mortality rate was 43% The mortality rate in patients with spontaneous meningitis was higher than that in patients with post-traumatic or postoperative meningitis. Factors that adversely affected mortality were age over 60, diabetes mellirus, and severe neurological deficits on admission. The use of third-generation cephalosporins did not reduce the mortality rate.

Original languageEnglish
Pages (from-to)95-102
Number of pages8
JournalScandinavian Journal of Infectious Diseases
Volume26
Issue number1
DOIs
StatePublished - 1994
Externally publishedYes

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