Lambert-Eaton myasthenic syndrome: Report of a chinese patient

Y. F. Tseng, L. M. Tang, R. K. Lyu*, S. T. Chen

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review


A 55-year-old man, with Lambert-Eaton myasthenic syndrome (LEMS) and small cell lung cancer, developed proximal weakness of limbs and autonomic dysfunction. Detailed electrophysiological studies revealed small compound muscle action potential amplitudes, decremental responses to 3Hz and incremental responses to maximal voluntary contractions. A 20Hz repetitive nerve stimulation (RNS) for 1 second revealed decremental responses. Results of this 20Hz high rate RNS were contradictory features seen in patients with LEMS. However, both prolonged 20Hz RNS for 5 seconds and 50Hz RNS for 1 second revealed incremental responses and confirmed the diagnosis. Thus, 50Hz RNS was more sensitive than 20Hz and sometimes prolonged 20Hz RNS is indicated, when documenting the disease.

Original languageEnglish
Pages (from-to)243-246
Number of pages4
JournalActa Neurologica Taiwanica
Issue number3
StatePublished - 2000
Externally publishedYes


  • Lambert-Eaton myasthenic syndrome
  • Postexercise facilitation
  • Repetitive nerve stimulation


Dive into the research topics of 'Lambert-Eaton myasthenic syndrome: Report of a chinese patient'. Together they form a unique fingerprint.

Cite this