L&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen

S. M. Hsu; Y. S. Ho; P. J. Li; J. Monheit; H. J. Ree; K. Sheibani; C. D. Winberg

L&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen

S. M. Hsu
, Y. S. Ho
, P. J. Li
, J. Monheit
, H. J. Ree
, K. Sheibani
, C. D. Winberg

University of Texas Health Science Center at Houston

Research output: Contribution to journal › Journal Article › peer-review

31 Scopus citations

Abstract

Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. however, the authors found that after neuraminidase treatment for removal of sialic acid, the L&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.

Original language	English
Pages (from-to)	199-203
Number of pages	5
Journal	American Journal of Pathology
Volume	122
Issue number	2
State	Published - 1986
Externally published	Yes

Cite this

@article{31aa1ad391d345c5be7de8e91295f10e,

title = "L\&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen",

abstract = "Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L\&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. however, the authors found that after neuraminidase treatment for removal of sialic acid, the L\&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L\&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.",

author = "Hsu, \{S. M.\} and Ho, \{Y. S.\} and Li, \{P. J.\} and J. Monheit and Ree, \{H. J.\} and K. Sheibani and Winberg, \{C. D.\}",

year = "1986",

language = "英语",

volume = "122",

pages = "199--203",

journal = "American Journal of Pathology",

issn = "0002-9440",

publisher = "Elsevier Inc.",

number = "2",

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TY - JOUR

T1 - L&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen

AU - Hsu, S. M.

AU - Ho, Y. S.

AU - Li, P. J.

AU - Monheit, J.

AU - Ree, H. J.

AU - Sheibani, K.

AU - Winberg, C. D.

PY - 1986

Y1 - 1986

N2 - Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. however, the authors found that after neuraminidase treatment for removal of sialic acid, the L&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.

AB - Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. however, the authors found that after neuraminidase treatment for removal of sialic acid, the L&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.

UR - https://www.scopus.com/pages/publications/0022610767

M3 - 文章

C2 - 3511719

AN - SCOPUS:0022610767

SN - 0002-9440

VL - 122

SP - 199

EP - 203

JO - American Journal of Pathology

JF - American Journal of Pathology

IS - 2

ER -

L&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen

Abstract

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