Leiomyomatosis peritonealis disseminata (LPD) with acute ascites induced by gonadotropin-releasing hormone (GnRH) agonist: A case report

C. W. Tseng*, C. C. ChangChien, J. W. Lin, T. Y. Hsu, S. Y. Chang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations

Abstract

Leiomyomatosis peritonealis disseminata (LPD) is a rare disorder characterized by the development of numerous leiomyomata throughout the peritoneal cavity. We present a case of a 29-year-old woman who had LPD with acute ascites induced by a GnRH agonist (Supremon; buserelin acetate nasal solution 400 μg/per day). We found abdominal wall leiomyomata under the left rectus muscle. Because the disorder tended to recur with acute ascites in this patient, castration was performed to eliminate the hormonal stimulation of tumor growth. We suggest postponing hormone replacement therapy post-operatively for 6 months, and we recommend close follow-up to prevent tumor recurrence and hypoestrogenism.

Original languageEnglish
Pages (from-to)352-357
Number of pages6
JournalChang Gung Medical Journal
Volume19
Issue number4
StatePublished - 1996
Externally publishedYes

Keywords

  • GnRH agonist
  • abdominal wall leiomyomata
  • acute ascites
  • leiomyomatosis peritonealis disseminata

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