Abstract
We report a case of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum), an uncommon disorder of uncertain pathogenesis characterized by disarrangement of the normal cerebellar laminar cytoarchitecture. A 40-year-old man was admitted because of vomiting and syncope of a few days' duration, and a 2-month history of intermittent headaches and unsteady gait. A computed tomographic scan of the patient's head showed obstructive hydrocephalus due to displacement of the fourth ventricle by a large, nonenhancing cerebellar mass. The magnetic resonance images of the brain also revealed a space-occupying lesion within the right cerebellum with unusual septation. After surgery, the histologic examination confirmed the diagnosis of Lhermitte-Duclos disease. This is the first report of Lhermitte-Duclos disease in Taiwan.
| Original language | English |
|---|---|
| Pages (from-to) | 649-652 |
| Number of pages | 4 |
| Journal | Journal of the Formosan Medical Association |
| Volume | 97 |
| Issue number | 9 |
| State | Published - 09 1998 |
Keywords
- Cerebellar ultrastructure
- Dysplastic gangliocytoma
- Immunohistochemistry
- Lhermitte-Duclos disease
- Magnetic resonance imaging