Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

Li Jen Hsin; Wan Ni Lin; Tuan Jen Fang; Li Ang Lee; Chung Jan Kang; Bing Shan Huang; Chien Yu Lin; Kang Hsing Fan; Ngan Ming Tsang; Cheng Lung Hsu; Joseph Tung Chieh Chang; Chun Ta Liao; Tzu Chen Yen; Kai Ping Chang; Hsiu Feng Chuang; Hsueh Yu Li

doi:10.1002/hed.24873

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

Li Jen Hsin, Wan Ni Lin, Tuan Jen Fang^*, Li Ang Lee, Chung Jan Kang, Bing Shan Huang, Chien Yu Lin, Kang Hsing Fan, Ngan Ming Tsang, Cheng Lung Hsu, Joseph Tung Chieh Chang, Chun Ta Liao, Tzu Chen Yen, Kai Ping Chang, Hsiu Feng Chuang, Hsueh Yu Li

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

2 Scopus citations

Abstract

Background: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). Methods: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times. Results: Most voice laboratory parameters worsened during the first month, then recovered to baseline after 6 months. The QLQ-H&N35 speech subscale was significantly improved. Among the voice laboratory parameters, pretreatment harmonics-to-noise ratio was an independent predictor (P =.041) for improvement on the speech subscale at the endpoint. Conclusion: Despite an initial deterioration of voice and QOL in the first month, patients who underwent TLM recovered to a plateau since the sixth month and then to better than preoperative status afterward. A greater improvement in QOL was seen in patients with poorer baseline voice quality.

Original language	English
Pages (from-to)	2070-2078
Number of pages	9
Journal	Head and Neck
Volume	39
Issue number	10
DOIs	https://doi.org/10.1002/hed.24873
State	Published - 10 2017

Bibliographical note

Publisher Copyright:
© 2017 Wiley Periodicals, Inc.

Keywords

glottic cancer
quality of life
recovery kinetics
transoral laser microsurgery
voice

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/hed.24873

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Hsin, L. J., Lin, W. N., Fang, T. J., Lee, L. A., Kang, C. J., Huang, B. S., Lin, C. Y., Fan, K. H., Tsang, N. M., Hsu, C. L., Chang, J. T. C., Liao, C. T., Yen, T. C., Chang, K. P., Chuang, H. F., & Li, H. Y. (2017). Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery. Head and Neck, 39(10), 2070-2078. https://doi.org/10.1002/hed.24873

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title = "Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery",

abstract = "Background: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). Methods: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times. Results: Most voice laboratory parameters worsened during the first month, then recovered to baseline after 6 months. The QLQ-H&N35 speech subscale was significantly improved. Among the voice laboratory parameters, pretreatment harmonics-to-noise ratio was an independent predictor (P =.041) for improvement on the speech subscale at the endpoint. Conclusion: Despite an initial deterioration of voice and QOL in the first month, patients who underwent TLM recovered to a plateau since the sixth month and then to better than preoperative status afterward. A greater improvement in QOL was seen in patients with poorer baseline voice quality.",

keywords = "glottic cancer, quality of life, recovery kinetics, transoral laser microsurgery, voice",

author = "Hsin, {Li Jen} and Lin, {Wan Ni} and Fang, {Tuan Jen} and Lee, {Li Ang} and Kang, {Chung Jan} and Huang, {Bing Shan} and Lin, {Chien Yu} and Fan, {Kang Hsing} and Tsang, {Ngan Ming} and Hsu, {Cheng Lung} and Chang, {Joseph Tung Chieh} and Liao, {Chun Ta} and Yen, {Tzu Chen} and Chang, {Kai Ping} and Chuang, {Hsiu Feng} and Li, {Hsueh Yu}",

note = "Publisher Copyright: {\textcopyright} 2017 Wiley Periodicals, Inc.",

year = "2017",

month = oct,

doi = "10.1002/hed.24873",

language = "英语",

volume = "39",

pages = "2070--2078",

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AU - Hsin, Li Jen

AU - Lin, Wan Ni

AU - Fang, Tuan Jen

AU - Lee, Li Ang

AU - Kang, Chung Jan

AU - Huang, Bing Shan

AU - Lin, Chien Yu

AU - Fan, Kang Hsing

AU - Tsang, Ngan Ming

AU - Hsu, Cheng Lung

AU - Chang, Joseph Tung Chieh

AU - Liao, Chun Ta

AU - Yen, Tzu Chen

AU - Chang, Kai Ping

AU - Chuang, Hsiu Feng

AU - Li, Hsueh Yu

PY - 2017/10

Y1 - 2017/10

N2 - Background: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). Methods: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times. Results: Most voice laboratory parameters worsened during the first month, then recovered to baseline after 6 months. The QLQ-H&N35 speech subscale was significantly improved. Among the voice laboratory parameters, pretreatment harmonics-to-noise ratio was an independent predictor (P =.041) for improvement on the speech subscale at the endpoint. Conclusion: Despite an initial deterioration of voice and QOL in the first month, patients who underwent TLM recovered to a plateau since the sixth month and then to better than preoperative status afterward. A greater improvement in QOL was seen in patients with poorer baseline voice quality.

AB - Background: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). Methods: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times. Results: Most voice laboratory parameters worsened during the first month, then recovered to baseline after 6 months. The QLQ-H&N35 speech subscale was significantly improved. Among the voice laboratory parameters, pretreatment harmonics-to-noise ratio was an independent predictor (P =.041) for improvement on the speech subscale at the endpoint. Conclusion: Despite an initial deterioration of voice and QOL in the first month, patients who underwent TLM recovered to a plateau since the sixth month and then to better than preoperative status afterward. A greater improvement in QOL was seen in patients with poorer baseline voice quality.

KW - glottic cancer

KW - quality of life

KW - recovery kinetics

KW - transoral laser microsurgery

KW - voice

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U2 - 10.1002/hed.24873

DO - 10.1002/hed.24873

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SN - 1043-3074

VL - 39

SP - 2070

EP - 2078

JO - Head and Neck

JF - Head and Neck

IS - 10

ER -

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

Abstract

Bibliographical note

Keywords

UN SDGs

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