Life-threatening esophageal variceal bleeding due to proteins C, S deficiency requiring esophagogastric devascularization: A case report

Y. M. Hsieh, S. M. Sheen-Chen, S. F. Ko, W. F. Lo, C. L. Lin*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

Abstract

Proteins C and S are important for the prevention of intravascular blood clotting, and patients with deficiency of these proteins have a higher risk of developing diffuse venous thrombosis. However, the onset is usually in childhood and the thrombosis is rare in portal system. Here we report an adult with this rare disease causing life-threatening esophageal variceal bleeding due to thrombosis of the portal venous system. For treatment of such bleeding which has failed in response to pharmacological treatment and endoscopic sclerotherapy, esophagogastric devascularization, gastric stapling and splenectomy are required.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalZhonghua Minguo wai ke yi xue hui za zhi
Volume34
Issue number1
StatePublished - 2001
Externally publishedYes

Keywords

  • Devascularization
  • Esophageal varices
  • Portal hypertension
  • Protein C
  • Protein S

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