Liquid chromatography-mass spectrometry in metabolite profiling

Chiun Gung Juo; Daniel Tsun Yee Chiu; Ming Shi Shiao

doi:10.1002/biof.5520340207

Liquid chromatography-mass spectrometry in metabolite profiling

Chiun Gung Juo, Daniel Tsun Yee Chiu, Ming Shi Shiao^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Recent advances in the use of liquid chromatography-mass spectrometry for the study of metabolomics are reviewed. Sample preparations of biofluids and practical aspects of ultra-high pressure liquid chromatography are discussed. Applicability of different kinds of mass spectrometers for metabolite profiling is described. New tools-ion mobility spectroscopy and automated chip-based nanoelectrospray system with potentials to be applied in the metabolomics analysis are described.

Original language	English
Pages (from-to)	159-169
Number of pages	11
Journal	BioFactors
Volume	34
Issue number	2
DOIs	https://doi.org/10.1002/biof.5520340207
State	Published - 2008
Externally published	Yes

Keywords

Ion mobility spectroscopy
LC-MS
Metabolite profiling
Metabolomics
UHPLC

Access to Document

10.1002/biof.5520340207

Cite this

@article{a6a026788cfc4a8eb18d59ce3eec9999,

title = "Liquid chromatography-mass spectrometry in metabolite profiling",

abstract = "Recent advances in the use of liquid chromatography-mass spectrometry for the study of metabolomics are reviewed. Sample preparations of biofluids and practical aspects of ultra-high pressure liquid chromatography are discussed. Applicability of different kinds of mass spectrometers for metabolite profiling is described. New tools-ion mobility spectroscopy and automated chip-based nanoelectrospray system with potentials to be applied in the metabolomics analysis are described.",

keywords = "Ion mobility spectroscopy, LC-MS, Metabolite profiling, Metabolomics, UHPLC",

author = "Juo, {Chiun Gung} and Chiu, {Daniel Tsun Yee} and Shiao, {Ming Shi}",

year = "2008",

doi = "10.1002/biof.5520340207",

language = "英语",

volume = "34",

pages = "159--169",

journal = "BioFactors",

issn = "0951-6433",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - Liquid chromatography-mass spectrometry in metabolite profiling

AU - Juo, Chiun Gung

AU - Chiu, Daniel Tsun Yee

AU - Shiao, Ming Shi

PY - 2008

Y1 - 2008

N2 - Recent advances in the use of liquid chromatography-mass spectrometry for the study of metabolomics are reviewed. Sample preparations of biofluids and practical aspects of ultra-high pressure liquid chromatography are discussed. Applicability of different kinds of mass spectrometers for metabolite profiling is described. New tools-ion mobility spectroscopy and automated chip-based nanoelectrospray system with potentials to be applied in the metabolomics analysis are described.

AB - Recent advances in the use of liquid chromatography-mass spectrometry for the study of metabolomics are reviewed. Sample preparations of biofluids and practical aspects of ultra-high pressure liquid chromatography are discussed. Applicability of different kinds of mass spectrometers for metabolite profiling is described. New tools-ion mobility spectroscopy and automated chip-based nanoelectrospray system with potentials to be applied in the metabolomics analysis are described.

KW - Ion mobility spectroscopy

KW - LC-MS

KW - Metabolite profiling

KW - Metabolomics

KW - UHPLC

UR - http://www.scopus.com/inward/record.url?scp=69449084658&partnerID=8YFLogxK

U2 - 10.1002/biof.5520340207

DO - 10.1002/biof.5520340207

M3 - 文献综述

C2 - 19706981

AN - SCOPUS:69449084658

SN - 0951-6433

VL - 34

SP - 159

EP - 169

JO - BioFactors

JF - BioFactors

IS - 2

ER -

Liquid chromatography-mass spectrometry in metabolite profiling

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this