Literature- and Experience-Based Consensus for Acute Post-operative Endophthalmitis and Endogenous Endophthalmitis in Taiwan

Cheng Yung Lee, Shwu Jiuan Sheu, San Ni Chen, Cheng Kuo Cheng, Hsi Kung Kuo, De Kuang Hwang, Chien Hsiung Lai, Wei Chun Chan, Yi Ting Hsieh, Chang Hao Yang*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

Abstract

Clinical practices on acute post-operative and endogenous endophthalmitis (EnE) are highly variable among clinicians due to a lack of up-to-date, high-quality evidential support. An expert consensus is thus much needed. A panel consisting of ten retinal specialists in Taiwan was organized. They evaluated relevant literature and developed key questions regarding acute post-operative and EnE that are cardinal for practice but yet to have conclusive evidence. The panel then attempted to reach consensus on all the key questions accordingly. There were eight key questions proposed and their respective consensus statements were summarized as follows: Gram staining and culture are still the standard procedures for the diagnosis of endophthalmitis. Vitrectomy is recommended to be performed earlier than the timing proposed by the Endophthalmitis Vitrectomy Study (EVS). Routine intracameral antibiotic injection for post-cataract surgery endophthalmitis prophylaxis is not recommended because of potential compounding error hazards and a lack of support from high-quality studies. Routine fundus examination is recommended for all patients with pyogenic liver abscess. In EnE, vitrectomy is recommended if diffused and dense vitritis is present, or if the disease progresses. These consensus statements may work as handy guidance or reference for clinical practices of acute post-operative and EnE.

Original languageEnglish
Pages (from-to)1-19
Number of pages19
JournalOphthalmology and Therapy
Volume13
Issue number1
DOIs
StatePublished - 01 2024

Bibliographical note

© 2023. The Author(s).

Keywords

  • Acute post-operative endophthalmitis
  • Endogenous endophthalmitis (EnE)
  • Expert consensus
  • Taiwan

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