Liver transplantation from an uncontrolled non-heart-beating donor maintained on extracorporeal membrane oxygenation

C. C. Wang, S. H. Wang, C. C. Lin, Y. W. Liu, C. C. Yong, C. H. Yang, K. C. Huang, T. S. Lin, B. Jawan, Y. F. Cheng, H. L. Eng, A. M. Concejero, C. L. Chen*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

34 Scopus citations

Abstract

Liver transplantation, a definitive treatment for end-stage liver disease, has achieved excellent results. However, potential recipients on the waiting list outnumber donors. To expand the donor pool, marginal grafts from older donors, steatotic livers, and non-heart-beating liver donors (NHBD) have been used for transplantation. Reducing the warm ischemia time of NHBD is the critical factor in organs preservation. Liver transplantation using grafts from NHBD have been reported to display a high incidence of primary graft nonfunction and biliary complications. The authors report a liver graft donor who was maintained on extracorporeal membrane oxygenation (ECMO) after successful cardiopulmonary resuscitation. Core body temperature was 5°C. Procurement of the liver using a rapid flush technique was performed 4 hours after instituting ECMO. Graft function recovered fully after transplantation. In conclusion, ECMO may be used to reduce warm ischemia time in liver grafts obtained from uncontrolled NHBD, thereby increasing graft salvage rates.

Original languageEnglish
Pages (from-to)4331-4333
Number of pages3
JournalTransplantation Proceedings
Volume37
Issue number10
DOIs
StatePublished - 12 2005
Externally publishedYes

Fingerprint

Dive into the research topics of 'Liver transplantation from an uncontrolled non-heart-beating donor maintained on extracorporeal membrane oxygenation'. Together they form a unique fingerprint.

Cite this