Living donor liver transplantation: The Asian perspective

Yu Fan Cheng, Chun Yen Yu, Hsin You Ou, Leo Leung Chit Tsang, Tung Liang Huang, Tai Yi Chen, Allan Concejero, Chih Chi Wang, Shih Ho Wang, Tsan Shiun Lin, Yueh Wei Liu, Chin Hsiang Yang, Chee Chien Yong, King Wah Chiu, Bruno Jawan, Hock Liew Eng, Chao Long Chen*, William Wei Sharr, Chung Mau Lo, Sumihito TamuraYasuhiko Sugawara, Norihiro Kokudo, Kwang Woong Lee, Nam Joon Yi, Kyung Suk Suh, Deok Bog Moon, Sung Gyu Lee, Chul Soo Ahn, Shin Huang, Ki Hun Kim, Tae Yong Ha, Gi Wong Song, Dong Hwan Jung, Gil Chun Park, Jung Man Namkoong, Hyung Woo Park, Yo Han Park, Cheon Soo Park, Kyw Bo Sung, Gi Young Ko, Dong Il Gwon, Toskimi Kaido, Kohei Ogawa, Yasuhiro Fujimoto, Takashi Ito, Koji Toniyama, Akira Mori, Yasuhiro Ogura, Shinji Uemoto, Anthony Q. Yap, Yu Hung Lin, Chun Yi Liu, Yuan Cheng Chiang, Chih Chi Lin, Milljae Shin, Jae Won Joh, Catherine Kabiling, Tsung Hui Hu, Sung Hwa Kang, Bo Hyun Jung, Young Rok Choi, See Ching Chan

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations

Abstract

Preoperative evaluation of donors for living-donor liver transplantation aims to select a suitable donor with optimal graft quality and to ensure donor safety. Hepatic steatosis, a common finding in living liver donors, not only influences the outcome of liver transplantation for the recipient but also affects the recovery of the living donor after partial hepatectomy. Histopathologic analysis is the reference standard to detect and quantify fat in the liver, but it is invasive, and results are vulnerable to sampling error. Imaging can be repeated regularly and allows assessment of the entire liver, thus avoiding sampling error. Selection of appropriate imaging methods demands understanding of their advantages and limitations and the suitable clinical setting. This article describes potential clinical applications for liver fat quantification of imaging methods for fat detection and quantification, with an emphasis on the advantages and limitations of ultrasonography, computed tomography, and magnetic resonance imaging for quantifying liver fat.

Original languageEnglish
Pages (from-to)S3-S6
JournalTransplantation
Volume97
Issue number8
DOIs
StatePublished - 27 04 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Copyright 2014 Lippincott Williams & Wilkins.

Keywords

  • CT
  • Fatty liver
  • Living donor liver transplantation
  • MR
  • Ultrasound

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