Local dermal hypersensitivity from dobutamine hydrochloride (Dobutrex solution) injection

C. C. Wu; W. J. Chen; J. J. Cheng; Y. Y. Hsieh; W. P. Lien

doi:10.1378/chest.99.6.1547

Local dermal hypersensitivity from dobutamine hydrochloride (Dobutrex solution) injection

C. C. Wu^*, W. J. Chen, J. J. Cheng, Y. Y. Hsieh, W. P. Lien

^*Corresponding author for this work

National Taiwan University

Research output: Contribution to journal › Journal Article › peer-review

14 Scopus citations

Abstract

Two patients had local dermal hypersensitivity at the site of dobutamine hydrochloride (Dobutrex solution) injection. Such local dermal lesions characterized by erythema, pruritus, and phlebitis with or without bullae formation have not been reported previously (to our knowledge). Hypersensitivity reaction to sulfites as a possible mechanism of the dermal lesions was substantiated further by skin tests and peripheral eosinophilia. Oral antihistamine therapy can minimize such a minor but bothersome problem.

Original language	English
Pages (from-to)	1547-1548
Number of pages	2
Journal	Chest
Volume	99
Issue number	6
DOIs	https://doi.org/10.1378/chest.99.6.1547
State	Published - 1991
Externally published	Yes

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title = "Local dermal hypersensitivity from dobutamine hydrochloride (Dobutrex solution) injection",

abstract = "Two patients had local dermal hypersensitivity at the site of dobutamine hydrochloride (Dobutrex solution) injection. Such local dermal lesions characterized by erythema, pruritus, and phlebitis with or without bullae formation have not been reported previously (to our knowledge). Hypersensitivity reaction to sulfites as a possible mechanism of the dermal lesions was substantiated further by skin tests and peripheral eosinophilia. Oral antihistamine therapy can minimize such a minor but bothersome problem.",

author = "Wu, {C. C.} and Chen, {W. J.} and Cheng, {J. J.} and Hsieh, {Y. Y.} and Lien, {W. P.}",

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AU - Chen, W. J.

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AU - Hsieh, Y. Y.

AU - Lien, W. P.

PY - 1991

Y1 - 1991

N2 - Two patients had local dermal hypersensitivity at the site of dobutamine hydrochloride (Dobutrex solution) injection. Such local dermal lesions characterized by erythema, pruritus, and phlebitis with or without bullae formation have not been reported previously (to our knowledge). Hypersensitivity reaction to sulfites as a possible mechanism of the dermal lesions was substantiated further by skin tests and peripheral eosinophilia. Oral antihistamine therapy can minimize such a minor but bothersome problem.

AB - Two patients had local dermal hypersensitivity at the site of dobutamine hydrochloride (Dobutrex solution) injection. Such local dermal lesions characterized by erythema, pruritus, and phlebitis with or without bullae formation have not been reported previously (to our knowledge). Hypersensitivity reaction to sulfites as a possible mechanism of the dermal lesions was substantiated further by skin tests and peripheral eosinophilia. Oral antihistamine therapy can minimize such a minor but bothersome problem.

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DO - 10.1378/chest.99.6.1547

M3 - 文章

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JF - Chest

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ER -

Local dermal hypersensitivity from dobutamine hydrochloride (Dobutrex solution) injection

Abstract

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