Long-term (36-63 month) clinical and echocardiographic follow-up after Inoue balloon mitral commissurotomy

Kean Wah Lau*, Zee Pin Ding, Susan Quek, Veronica Kwok, Jui Sung Hung

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

13 Scopus citations


Although Inoue balloon mitral commissurotomy (BMC) offers excellent short-term results, there remains a paucity of data on its long-term (≤3 yr) outcome. We therefore analyzed the outcome of 68 consecutive patients who had regular long-term clinical and serial echocardiographic follow-up of ≤3 yr after successful BMC. The procedure provided significant improvements in transmitral valve gradient (13 ± 6 mmHg before to 5 ± 2 mmHg after BMC, P = 0.0001), left atrial pressure (21 ± 6 mmHg before to 14 ± 5 mmHg after BMC, P = 0.0001), and mitral valve area (0.8 ± 0.2 cm2 before to 1.7 ± 0.4 cm2 after BMC, P = 0.0001) without incurring > grade 2+ angiographic mitral regurgitation. At a mean follow-up of 44 ± 9 mos (range, 36-63 mo), functional benefits were maintained in 91% of patients. Serial echocardiographic evaluations performed in 97% of patients revealed a restenosis rate of 15% (defined as a loss of >50% initial gain in valve area or a valve area of <1.5 cm2). No strokes or deaths were encountered. Of the 15 clinical, echocardiographic, and procedural variables analyzed In a multivariate model, only the presence of chronic atrial fibrillation was an independent correlate of restenosis (P < 0.05). It was clearly more common in patients with than those without restenosis (100% with vs. 57%, respectively, P = 0.009). In conclusion, our study shows that BMC confers maintained long- term functional benefits and a low anatomic restenosis rate ≤3 yr after BMC.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalCatheterization and Cardiovascular Diagnosis
Issue number1
StatePublished - 01 1998
Externally publishedYes


  • Balloon mitral valvuloplasty
  • Mitral stenosis
  • Restenosis


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