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Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2

  • Lian Dee Ler
  • , Sujoy Ghosh
  • , Xiaoran Chai
  • , Aye Aye Thike
  • , Hong Lee Heng
  • , Ee Yan Siew
  • , Sucharita Dey
  • , Liang Kai Koh
  • , Jing Quan Lim
  • , Weng Khong Lim
  • , Swe Swe Myint
  • , Jia Liang Loh
  • , Pauline Ong
  • , Xin Xiu Sam
  • , Dachuan Huang
  • , Tony Lim
  • , Puay Hoon Tan
  • , Sanjanaa Nagarajan
  • , Christopher Wai Sam Cheng
  • , Henry Ho
    • Lay Guat Ng, John Yuen, Po Hung Lin, Cheng Keng Chuang, Ying Hsu Chang, Wen Hui Weng, Steven G. Rozen, Patrick Tan, Caretha L. Creasy, See Tong Pang, Michael T. Mccabe, Song Ling Poon, Bin Tean Teh*
*Corresponding author for this work
  • National Cancer Centre
  • Duke-NUS Medical School
  • National University of Singapore
  • Singapore General Hospital
  • Chang Gung University
  • National Taipei University of Technology
  • Agency for Science, Technology and Research, Singapore
  • GlaxoSmithKline

Research output: Contribution to journal › Journal Article › peer-review

183 Scopus citations

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Biochemistry, Genetics and Molecular Biology