Low cost and high specific anesthetic biosensors with functionally imprinted nanocavities on polymer films

Chien Chong Hong*, Chih Chung Lin, Chian Lang Hong, Po Hsiang Chang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

This paper presents low cost and high specific anesthetic biosensors with functionally imprinted nanocavities on polymer films. Propofol (2,6-di-isopropylphenol) is an intravenous anesthetic, widely used in induction of anesthesia, total intravenous anesthesia and sedation of intensive care unit patients. Although the propofol concentration in blood can be detected by high-performance liquid chromatography and/or gas chromatography, these methods are time-consuming and not ease of access. In this work, we control the morphology of imprinted nanocavities on molecularly imprinted biosensors by adjusting polymer composition. Our developed biosensors have been compared with a conventional spectrophotometer to investigate surface morphology and performance of the anesthetic biosensors. The performance of the anesthetic biosensors can be enhanced by adjusting morphology of imprinted nanocavities. The newly developed biosensors have been characterized using our developed optofluidic microsystem.

Original languageEnglish
Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages1196-1199
Number of pages4
DOIs
StatePublished - 2011
Externally publishedYes
Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
Duration: 05 06 201109 06 2011

Publication series

Name2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Conference

Conference2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/TerritoryChina
CityBeijing
Period05/06/1109/06/11

Keywords

  • anesthetic propofol
  • biosensors
  • microfluidic biochips
  • molecularly imprinted polymers

Fingerprint

Dive into the research topics of 'Low cost and high specific anesthetic biosensors with functionally imprinted nanocavities on polymer films'. Together they form a unique fingerprint.

Cite this