Low-grade serous ovarian cancer: State of the science

Brian Slomovitz; Charlie Gourley; Mark S. Carey; Anais Malpica; Ie Ming Shih; David Huntsman; Amanda N. Fader; Rachel N. Grisham; Matthew Schlumbrecht; Charlotte C. Sun; Jane Ludemann; Gail Austin Cooney; Robert Coleman; Anil K. Sood; Haider Mahdi; Kwong K. Wong; Allan Covens; David M. O'Malley; Fabrice Lecuru; Lauren P. Cobb; Thomas A. Caputo; Taymaa May; Marilyn Huang; John Siemon; Marta Llauradó Fernández; Isabelle Ray-Coquard; David M. Gershenson

doi:10.1016/j.ygyno.2019.12.033

Low-grade serous ovarian cancer: State of the science

Brian Slomovitz^*, Charlie Gourley, Mark S. Carey, Anais Malpica, Ie Ming Shih, David Huntsman, Amanda N. Fader, Rachel N. Grisham, Matthew Schlumbrecht, Charlotte C. Sun, Jane Ludemann, Gail Austin Cooney, Robert Coleman, Anil K. Sood, Haider Mahdi, Kwong K. Wong, Allan Covens, David M. O'Malley, Fabrice Lecuru, Lauren P. CobbThomas A. Caputo, Taymaa May, Marilyn Huang, John Siemon, Marta Llauradó Fernández, Isabelle Ray-Coquard, David M. Gershenson

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

76 Scopus citations

Abstract

In January 2019, a group of basic, translational, and clinical investigators and patient advocates assembled in Miami, Florida, to discuss the current state of the science of low-grade serous carcinoma of the ovary or peritoneum–a rare ovarian cancer subtype that may arise de novo or following a diagnosis of serous borderline tumor. The purpose of the conference was to review current knowledge, discuss ongoing research by established researchers, and frame critical questions or issues for future directions. Following presentations and discussions, the primary objective was to initiate future collaborations, uniform database platforms, laboratory studies, and clinical trials to better understand this disease and to advance clinical care outside the boundaries of single academic institutions. This review summarizes the state of the science in five principal categories: epidemiology and patient outcomes, pathology, translational research, patient care and clinical trials, and patients' perspective.

Original language	English
Pages (from-to)	715-725
Number of pages	11
Journal	Gynecologic Oncology
Volume	156
Issue number	3
DOIs	https://doi.org/10.1016/j.ygyno.2019.12.033
State	Published - 03 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.

Keywords

Epithelial ovarian cancer
Low-grade serous carcinoma of the ovary
Low-grade serous carcinoma of the peritoneum

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ygyno.2019.12.033

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Slomovitz, B., Gourley, C., Carey, M. S., Malpica, A., Shih, I. M., Huntsman, D., Fader, A. N., Grisham, R. N., Schlumbrecht, M., Sun, C. C., Ludemann, J., Cooney, G. A., Coleman, R., Sood, A. K., Mahdi, H., Wong, K. K., Covens, A., O'Malley, D. M., Lecuru, F., ... Gershenson, D. M. (2020). Low-grade serous ovarian cancer: State of the science. Gynecologic Oncology, 156(3), 715-725. https://doi.org/10.1016/j.ygyno.2019.12.033

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title = "Low-grade serous ovarian cancer: State of the science",

abstract = "In January 2019, a group of basic, translational, and clinical investigators and patient advocates assembled in Miami, Florida, to discuss the current state of the science of low-grade serous carcinoma of the ovary or peritoneum–a rare ovarian cancer subtype that may arise de novo or following a diagnosis of serous borderline tumor. The purpose of the conference was to review current knowledge, discuss ongoing research by established researchers, and frame critical questions or issues for future directions. Following presentations and discussions, the primary objective was to initiate future collaborations, uniform database platforms, laboratory studies, and clinical trials to better understand this disease and to advance clinical care outside the boundaries of single academic institutions. This review summarizes the state of the science in five principal categories: epidemiology and patient outcomes, pathology, translational research, patient care and clinical trials, and patients' perspective.",

keywords = "Epithelial ovarian cancer, Low-grade serous carcinoma of the ovary, Low-grade serous carcinoma of the peritoneum",

author = "Brian Slomovitz and Charlie Gourley and Carey, {Mark S.} and Anais Malpica and Shih, {Ie Ming} and David Huntsman and Fader, {Amanda N.} and Grisham, {Rachel N.} and Matthew Schlumbrecht and Sun, {Charlotte C.} and Jane Ludemann and Cooney, {Gail Austin} and Robert Coleman and Sood, {Anil K.} and Haider Mahdi and Wong, {Kwong K.} and Allan Covens and O'Malley, {David M.} and Fabrice Lecuru and Cobb, {Lauren P.} and Caputo, {Thomas A.} and Taymaa May and Marilyn Huang and John Siemon and Fern{\'a}ndez, {Marta Llaurad{\'o}} and Isabelle Ray-Coquard and Gershenson, {David M.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = mar,

doi = "10.1016/j.ygyno.2019.12.033",

language = "英语",

volume = "156",

pages = "715--725",

journal = "Gynecologic Oncology",

issn = "0090-8258",

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Slomovitz, B, Gourley, C, Carey, MS, Malpica, A, Shih, IM, Huntsman, D, Fader, AN, Grisham, RN, Schlumbrecht, M, Sun, CC, Ludemann, J, Cooney, GA, Coleman, R, Sood, AK, Mahdi, H, Wong, KK, Covens, A, O'Malley, DM, Lecuru, F, Cobb, LP, Caputo, TA, May, T, Huang, M, Siemon, J, Fernández, ML, Ray-Coquard, I & Gershenson, DM 2020, 'Low-grade serous ovarian cancer: State of the science', Gynecologic Oncology, vol. 156, no. 3, pp. 715-725. https://doi.org/10.1016/j.ygyno.2019.12.033

TY - JOUR

T1 - Low-grade serous ovarian cancer

T2 - State of the science

AU - Slomovitz, Brian

AU - Gourley, Charlie

AU - Carey, Mark S.

AU - Malpica, Anais

AU - Shih, Ie Ming

AU - Huntsman, David

AU - Fader, Amanda N.

AU - Grisham, Rachel N.

AU - Schlumbrecht, Matthew

AU - Sun, Charlotte C.

AU - Ludemann, Jane

AU - Cooney, Gail Austin

AU - Coleman, Robert

AU - Sood, Anil K.

AU - Mahdi, Haider

AU - Wong, Kwong K.

AU - Covens, Allan

AU - O'Malley, David M.

AU - Lecuru, Fabrice

AU - Cobb, Lauren P.

AU - Caputo, Thomas A.

AU - May, Taymaa

AU - Huang, Marilyn

AU - Siemon, John

AU - Fernández, Marta Llauradó

AU - Ray-Coquard, Isabelle

AU - Gershenson, David M.

PY - 2020/3

Y1 - 2020/3

N2 - In January 2019, a group of basic, translational, and clinical investigators and patient advocates assembled in Miami, Florida, to discuss the current state of the science of low-grade serous carcinoma of the ovary or peritoneum–a rare ovarian cancer subtype that may arise de novo or following a diagnosis of serous borderline tumor. The purpose of the conference was to review current knowledge, discuss ongoing research by established researchers, and frame critical questions or issues for future directions. Following presentations and discussions, the primary objective was to initiate future collaborations, uniform database platforms, laboratory studies, and clinical trials to better understand this disease and to advance clinical care outside the boundaries of single academic institutions. This review summarizes the state of the science in five principal categories: epidemiology and patient outcomes, pathology, translational research, patient care and clinical trials, and patients' perspective.

AB - In January 2019, a group of basic, translational, and clinical investigators and patient advocates assembled in Miami, Florida, to discuss the current state of the science of low-grade serous carcinoma of the ovary or peritoneum–a rare ovarian cancer subtype that may arise de novo or following a diagnosis of serous borderline tumor. The purpose of the conference was to review current knowledge, discuss ongoing research by established researchers, and frame critical questions or issues for future directions. Following presentations and discussions, the primary objective was to initiate future collaborations, uniform database platforms, laboratory studies, and clinical trials to better understand this disease and to advance clinical care outside the boundaries of single academic institutions. This review summarizes the state of the science in five principal categories: epidemiology and patient outcomes, pathology, translational research, patient care and clinical trials, and patients' perspective.

KW - Epithelial ovarian cancer

KW - Low-grade serous carcinoma of the ovary

KW - Low-grade serous carcinoma of the peritoneum

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U2 - 10.1016/j.ygyno.2019.12.033

DO - 10.1016/j.ygyno.2019.12.033

M3 - 文献综述

C2 - 31969252

AN - SCOPUS:85078022671

SN - 0090-8258

VL - 156

SP - 715

EP - 725

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 3

ER -

Low-grade serous ovarian cancer: State of the science

Abstract

Bibliographical note

Keywords

UN SDGs

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