Macrophage pattern recognition receptors in immunity, homeostasis and self tolerance

Subhankar Mukhopadhyay, Annette Plüddemann, Siamon Gordon*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

48 Scopus citations

Abstract

Macrophages, a major component of innate immune defence, express a large repertoire of different classes of pattern recognition receptors and other surface antigens which determine the immunologic and homeostatic potential of these versatile cells. In the light of present knowledge of macrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system.

Original languageEnglish
Title of host publicationTarget Pattern Recognition in Innate Immunity
EditorsUday Kishore
Pages1-14
Number of pages14
DOIs
StatePublished - 2009
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume653
ISSN (Print)0065-2598

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