Macrophage receptors implicated in the "adaptive" form of innate immunity

D. M.E. Bowdish, M. S. Loffredo, S. Mukhopadhyay, Alberto Mantovani, S. Gordon*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

107 Scopus citations

Abstract

The adaptive component of innate immunity occurs during the course of infection when antigen presenting cells alter expression of soluble or surface associated pattern recognition receptors. This results in increased recognition of a broad spectrum of pathogens, enhancement of effector functions and altered regulation of the inflammatory response.

Original languageEnglish
Pages (from-to)1680-1687
Number of pages8
JournalMicrobes and Infection
Volume9
Issue number14-15
DOIs
StatePublished - 11 2007
Externally publishedYes

Keywords

  • Dectin-1
  • Innate immunity
  • Macrophages
  • Pentraxin
  • Scavenger receptors

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