Macrophages

Sigrid E.M. Heinsbroek, Siamon Gordon

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Macrophages are important for both tissue homeostasis and immunity. A great variety of macrophage subpopulations exist that are specialised in different functions eg, osteoclasts that remodel bone, inflammatory macrophages that orchestrate the immune response. As immune regulators macrophages recognise, internalise, degrade and present antigens. Different levels of macrophage activation can be distinguished and this influences the type of immune stimulators secreted by macrophages. Different pathogens have developed ways to evade the macrophage or influence macrophage function to their advantage.

Original languageEnglish
Title of host publicationImmunology of Fungal Infections
PublisherSpringer Netherlands
Pages3-25
Number of pages23
ISBN (Electronic)9781402054921
ISBN (Print)9781402054914
DOIs
StatePublished - 2007
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2007 Springer. All Rights Reserved.

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