Abstract
Paroxysmal nocturnal hemoglobinuria (PNH) is a blood cell disorder characterized by repeated intravascular hemolysis. Histologically, there is hemosiderin deposition in the proximal tubular cells of the renal cortex. We report a case of PNH with characteristic magnetic resonance findings. The signal intensity of the renal cortex was markedly decreased in various pulse sequences because of the T2-shortening paramagnetic effect of hemosiderin. The significance of signal intensity ratios between renal cortex and medulla, renal cortex and skeletal muscle are discussed. These ratios of the PNH patient are significantly different from those of normal controls (p = 0.0000).
| Original language | English |
|---|---|
| Pages (from-to) | 100-104 |
| Number of pages | 5 |
| Journal | Chang Gung Medical Journal |
| Volume | 17 |
| Issue number | 1 |
| State | Published - 03 1994 |
| Externally published | Yes |