Management of endometrial cancer in Asia: consensus statement from the Asian Oncology Summit 2009

Siriwan Tangjitgamol, Benjamin O. Anderson, Hui Ti See, Chawalit Lertbutsayanukul, Nakarin Sirisabya, Tarinee Manchana, Arunachalam Ilancheran, Khai Mun Lee, Siew Eng Lim, Yin Nin Chia, Efren Domingo, Young Tak Kim, Chyong Huey Lai, Ahmad Zailani Hatta Mohd Dali, Wisit Supakapongkul, Sarikapan Wilailak, Eng Hseon Tay, John Kavanagh*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations

Abstract

Endometrial cancer is one of the gynaecological cancers that carries good overall prognosis because it is often detected at early stages of disease. The International Federation of Gynecology and Obstetrics replaced clinical staging with surgical staging in 1988 and updated the system in 2009. Controversies remain regarding the recommended screening protocol for women with a high risk of endometrial cancer, the role and benefit of retroperitoneal lymph-node dissection, the necessity of ovarian resection, the benefit and type of adjuvant radiation therapy, and the safety of hormone-replacement therapy after treatment. This article reviews the available evidence for optimum management of endometrial cancer and how management strategies can be applied in Asian countries with different levels of health-care resource availability and economic development. An overview of the literature for endometrial-cancer screening, diagnosis, and management is discussed. Consensus statements are formulated on the basis of basic, limited, enhanced, and maximum health-care resource availability, using the framework provided by the Breast Health Global Initiative.

Original languageEnglish
Pages (from-to)1119-1127
Number of pages9
JournalThe Lancet Oncology
Volume10
Issue number11
DOIs
StatePublished - 11 2009

Keywords

  • ADJUVANT TREATMENT
  • FOLLOW-UP
  • INTERMEDIATE-RISK
  • MRC ASTEC
  • PELVIC RADIATION-THERAPY
  • PHASE-III TRIAL
  • POSTOPERATIVE RADIOTHERAPY
  • RANDOMIZED-TRIAL
  • REPLACEMENT THERAPY
  • STAGE-I

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