Massive pontine hemorrhagic transformation associated with an anticoagulant for basilar artery occlusion

Ming Chang Hsiao, Jiann Der Lee*, Meng Lee, Hsu Huei Weng

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations

Abstract

Symptomatic hemorrhagic transformation is common in supratentorial and cerebellar infarction, but is rare in brainstem infarction. It is seldom reported in basilar artery occlusion. Although early arterial recanalization by thrombolytic agent has became the new trend of treatment, for some neurologists anticoagulant is still a conventional alternative treatment of basilar artery occlusion, especially in longer-existing ischemic deficits. We report a case of massive pontine hemorrhage associated with enoxaparin (low-molecular-weight heparin) treatment for basilar artery occlusion. On the basis of the clinical information and neuroimaging, an embolism was the most likely cause of stroke. The case presented herein adds massive pontine hemorrhagic transformation to the list of possible complications of anticoagulants for basilar artery occlusion. Apart from no evidence-based benefit in treatment of basilar artery occlusion, anticoagulant may contribute to devastating hemorrhagic transformation.

Original languageEnglish
Pages (from-to)431-433
Number of pages3
JournalNeurology India
Volume54
Issue number4
DOIs
StatePublished - 01 10 2006

Keywords

  • Anticoagulants
  • Basilar artery occlusion
  • Enoxaparin
  • Hemorrhagic transformation

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