TY - JOUR
T1 - Medial canthal tophus associated with gout
AU - Yen, Chang Chu
AU - Yi, Yueh Hsieh
AU - Ma, Lih
PY - 2005/9
Y1 - 2005/9
N2 - PURPOSE: To report a case with a gouty tophus at the medial canthus. DESIGN: Observational case report. METHODS: Review of the clinical, laboratory, photographic, and pathologic records of a patient with a gouty tophus at the medial canthus. RESULTS: A 27-year-old man had a 3-year history of gouty arthritis and poorly controlled hyperuricemia. A medial canthal mass without discomfort developed gradually over 3 months. An excisional biopsy was performed, and the tissue was fixed in formalin for pathology. Analysis of a routine hematoxylin-and-eosin-stained section disclosed a multilobulated pseudocyst filled with amorphous eosinophilic material. Further staining with nonaqueous alcoholic eosin and viewed under a polarizing microscope indicated the presence of birefringent urate crystals. CONCLUSIONS: Gouty tophus can develop progressively at the medial canthus, especially in people with uncontrolled hyperuricemia. A formalin-fixed specimen, stained with nonaqueous alcoholic eosin, demonstrates abundant birefringent urate crystals under a polarizing microscope.
AB - PURPOSE: To report a case with a gouty tophus at the medial canthus. DESIGN: Observational case report. METHODS: Review of the clinical, laboratory, photographic, and pathologic records of a patient with a gouty tophus at the medial canthus. RESULTS: A 27-year-old man had a 3-year history of gouty arthritis and poorly controlled hyperuricemia. A medial canthal mass without discomfort developed gradually over 3 months. An excisional biopsy was performed, and the tissue was fixed in formalin for pathology. Analysis of a routine hematoxylin-and-eosin-stained section disclosed a multilobulated pseudocyst filled with amorphous eosinophilic material. Further staining with nonaqueous alcoholic eosin and viewed under a polarizing microscope indicated the presence of birefringent urate crystals. CONCLUSIONS: Gouty tophus can develop progressively at the medial canthus, especially in people with uncontrolled hyperuricemia. A formalin-fixed specimen, stained with nonaqueous alcoholic eosin, demonstrates abundant birefringent urate crystals under a polarizing microscope.
UR - http://www.scopus.com/inward/record.url?scp=24044440202&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2005.02.060
DO - 10.1016/j.ajo.2005.02.060
M3 - 文章
C2 - 16139012
AN - SCOPUS:24044440202
SN - 0002-9394
VL - 140
SP - 542
EP - 544
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 3
ER -