Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

Ying Chang Tung; Yu Chang Huang; Lung Sheng Wu; Chee Jen Chang; Pao Hsien Chu

doi:10.1111/jch.13035

Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

Ying Chang Tung, Yu Chang Huang, Lung Sheng Wu, Chee Jen Chang, Pao Hsien Chu^*

^*Corresponding author for this work

Chang Gung University

Research output: Contribution to journal › Journal Article › peer-review

14 Scopus citations

Abstract

Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

Original language	English
Pages (from-to)	983-989
Number of pages	7
Journal	Journal of Clinical Hypertension
Volume	19
Issue number	10
DOIs	https://doi.org/10.1111/jch.13035
State	Published - 10 2017

Bibliographical note

Publisher Copyright:
©2017 Wiley Periodicals, Inc.

Keywords

angiotensin II receptor blocker
dihydropyridine calcium channel blocker
fixed-dose combination
hypertension
major adverse cardiac event

Access to Document

10.1111/jch.13035

Cite this

@article{484b57434a304e95a26d9301676810b8,

title = "Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment",

abstract = "Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.",

keywords = "angiotensin II receptor blocker, dihydropyridine calcium channel blocker, fixed-dose combination, hypertension, major adverse cardiac event",

author = "Tung, {Ying Chang} and Huang, {Yu Chang} and Wu, {Lung Sheng} and Chang, {Chee Jen} and Chu, {Pao Hsien}",

note = "Publisher Copyright: {\textcopyright}2017 Wiley Periodicals, Inc.",

year = "2017",

month = oct,

doi = "10.1111/jch.13035",

language = "英语",

volume = "19",

pages = "983--989",

journal = "Journal of Clinical Hypertension",

issn = "1524-6175",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "10",

}

Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. / Tung, Ying Chang; Huang, Yu Chang; Wu, Lung Sheng et al.
In: Journal of Clinical Hypertension, Vol. 19, No. 10, 10.2017, p. 983-989.

Research output: Contribution to journal › Journal Article › peer-review

TY - JOUR

T1 - Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

AU - Tung, Ying Chang

AU - Huang, Yu Chang

AU - Wu, Lung Sheng

AU - Chang, Chee Jen

AU - Chu, Pao Hsien

PY - 2017/10

Y1 - 2017/10

N2 - Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

AB - Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

KW - angiotensin II receptor blocker

KW - dihydropyridine calcium channel blocker

KW - fixed-dose combination

KW - hypertension

KW - major adverse cardiac event

UR - http://www.scopus.com/inward/record.url?scp=85019987565&partnerID=8YFLogxK

U2 - 10.1111/jch.13035

DO - 10.1111/jch.13035

M3 - 文章

C2 - 28560786

AN - SCOPUS:85019987565

SN - 1524-6175

VL - 19

SP - 983

EP - 989

JO - Journal of Clinical Hypertension

JF - Journal of Clinical Hypertension

IS - 10

ER -

Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this