Melanoma-associated retinopathy

Chun Hsiu Liu, Nan Kai Wang, Ming Hui Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

3 Scopus citations

Abstract

A 63-year-old Taiwanese man with a history of cutaneous melanoma presented with a rapid onset of bilateral shimmering light and blurred vision. A fundoscopic examination was normal. However, visual field examination indicated generalized depression in both eyes. Scotopic rod-specific electroretinography (ERG) was undetectable and scotopic maximal combined-cone and rod-specific ERG showed the characteristics of negative ERG (a normal a-wave and a diminished b-wave, with the b-wave smaller than the a-wave), indicating dysfunction of the bipolar cells. Melanoma-associated retinopathy (MAR) was suspected and a systemic work-up gave a diagnosis of metastatic melanoma. This case shows the typical presentation of MAR. Greater awareness of MAR in patients with unexplained visual loss may help to identify an occult focus of metastatic melanoma.

Original languageEnglish
Pages (from-to)184-188
Number of pages5
JournalTaiwan Journal of Ophthalmology
Volume4
Issue number4
DOIs
StatePublished - 2014

Bibliographical note

Publisher Copyright:
© 2013, The Ophthalmologic Society of Taiwan.

Keywords

  • Electronegative electroretinography
  • Melanoma-associated retinopathy

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