Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease

Hsin Hsu Chen; Po Mai Liu; Chin Nam Bong; Yu Tsun Wu; Kuender D. Yang; Chih Lu Wang

Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease

Hsin Hsu Chen
, Po Mai Liu
, Chin Nam Bong
, Yu Tsun Wu
, Kuender D. Yang
, Chih Lu Wang^*

^*Corresponding author for this work

Chang Gung Memorial Hospital
Ping Tung Christian Hospital, Taiwan
Yunlin Huwei St. Joseph Hospital

Research output: Contribution to journal › Journal Article › peer-review

5 Scopus citations

Abstract

Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse steroid may be an alternative therapeutic option in KD which presents with possible life-threatening complications or failure to respond to high-dose IVIG infusion.

Original language	English
Pages (from-to)	149-152
Number of pages	4
Journal	Journal of Microbiology, Immunology and Infection
Volume	38
Issue number	2
State	Published - 04 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Drug pulse therapy
Intravenous immunoglobulins
Methylprednisolone
Mucocutaneous lymph node syndrome

Cite this

@article{abd346e40b8145d1b24761bc4d5c0423,

title = "Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease",

abstract = "Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse steroid may be an alternative therapeutic option in KD which presents with possible life-threatening complications or failure to respond to high-dose IVIG infusion.",

keywords = "Drug pulse therapy, Intravenous immunoglobulins, Methylprednisolone, Mucocutaneous lymph node syndrome",

author = "Chen, \{Hsin Hsu\} and Liu, \{Po Mai\} and Bong, \{Chin Nam\} and Wu, \{Yu Tsun\} and Yang, \{Kuender D.\} and Wang, \{Chih Lu\}",

year = "2005",

month = apr,

language = "英语",

volume = "38",

pages = "149--152",

journal = "Journal of Microbiology, Immunology and Infection",

issn = "1684-1182",

publisher = "Elsevier Ltd",

number = "2",

}

TY - JOUR

T1 - Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease

AU - Chen, Hsin Hsu

AU - Liu, Po Mai

AU - Bong, Chin Nam

AU - Wu, Yu Tsun

AU - Yang, Kuender D.

AU - Wang, Chih Lu

PY - 2005/4

Y1 - 2005/4

N2 - Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse steroid may be an alternative therapeutic option in KD which presents with possible life-threatening complications or failure to respond to high-dose IVIG infusion.

AB - Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse steroid may be an alternative therapeutic option in KD which presents with possible life-threatening complications or failure to respond to high-dose IVIG infusion.

KW - Drug pulse therapy

KW - Intravenous immunoglobulins

KW - Methylprednisolone

KW - Mucocutaneous lymph node syndrome

UR - https://www.scopus.com/pages/publications/19944372777

M3 - 文章

C2 - 15843862

AN - SCOPUS:19944372777

SN - 1684-1182

VL - 38

SP - 149

EP - 152

JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

IS - 2

ER -

Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease

Abstract

UN SDGs

Keywords

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