Microcellular injection molding and particulate leaching of thermoplastic polyurethane (TPU) scaffolds

Hao Yang Mi, Xin Jing, Lih Sheng Turng*, Xiang Fang Peng

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

Microcellular injection moldingand particulate leaching methods were combined to fabricate porousand interconnectedthermoplastic polyurethane (TPU) tissue engineering scaffolds. Water soluble polyvinyl alcohol (PVOH) and sodium chloride (NaCl) were used as porogens to improve the porosity and interconnectivity, as well as the hydrophilicity, of the scaffolds. The effect of each factor-namely, PVOH, NaCl, and microcellular injection molding-on scaffold morphology was investigated. It was found that the microcellular injection molding processwas effectiveatproducing high pore density and porosity. The addition of PVOH decreasedthe pore diameter and increasedthe pore density. Furthermore, scaffolds with NaCl and PVOH porogens hadbetter interconnectivity. The residual PVOH improved the hydrophilicity of the scaffold.

Original languageEnglish
Title of host publicationProceedings of PPS 2013 - 29th International Conference of the Polymer Processing Society, Conference Papers
PublisherAmerican Institute of Physics Inc.
Pages392-396
Number of pages5
ISBN (Print)9780735412279
DOIs
StatePublished - 2014
Externally publishedYes
Event29th International Conference of the Polymer Processing Society, PPS 2013 - Nuremberg, Germany
Duration: 15 07 201319 07 2013

Publication series

NameAIP Conference Proceedings
Volume1593
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference29th International Conference of the Polymer Processing Society, PPS 2013
Country/TerritoryGermany
CityNuremberg
Period15/07/1319/07/13

Keywords

  • microcellular injection molding
  • particulate leaching
  • Thermoplastic polyurethane
  • tissue scaffolds

Fingerprint

Dive into the research topics of 'Microcellular injection molding and particulate leaching of thermoplastic polyurethane (TPU) scaffolds'. Together they form a unique fingerprint.

Cite this