Abstract
This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications.
| Original language | English |
|---|---|
| Pages (from-to) | 9804-9830 |
| Number of pages | 27 |
| Journal | International Journal of Molecular Sciences |
| Volume | 16 |
| Issue number | 5 |
| DOIs | |
| State | Published - 29 04 2015 |
Bibliographical note
Publisher Copyright:© 2015 by the authors; licensee MDPI, Basel, Switzerland.
Keywords
- High throughput
- Impedance flow cytometry
- Microfluidics
- Single-cell electrical property analysis