Mifepristone-induced abortion in one horn and a growing fetus in another horn in a patient with a twin pregnancy in a bicornuate uterus

Objective: To report a case of mifepristone-induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in a bicornuate uterus. Design: Case report. Setting: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taiwan. Patient(s): A 31-year-old woman who conceived spontaneously presented with 37 days' gestation. Intervention(s): Mifepristone 600 mg orally followed by misoprostol 400 μg orally 2 days later. Main Outcome Measure(s): Termination of pregnancy. Result(s): Induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in the bicornuate uterus detected by ultrasound. Surgical abortion with vacuum curettage was performed, and menstruation resumed 1 month later. Conclusion(s): As medical abortion with mifepristone and misoprostol becomes more prevalent, more studies are necessary to establish the dosage and regimens for multiple pregnancies associated with uterine anomalies.