Abstract
An undeniable fact in nowadays technology is that tissue morphology has been of pivotal significance in vivo research. To mimic and maintain cell culture inside microenvironment on microfluidic chips, multiple stresses must be taken into account whereas it would rupture cell membrane from the outside environment and even deteriorate cell patterns. In this study, we used laminar-flow hydrogel for lobule-mimetic on the chip where it is mainly used to take shape for mimicking morphology of liver lobule tissue inside the 3D microfluidic chip. Meanwhile, cells are encapsulated by gelatin methacrylate (GelMA), which is a kind of hydrogels formed by polymerization.
| Original language | English |
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| Title of host publication | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1151-1152 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780692941836 |
| State | Published - 2020 |
| Externally published | Yes |
| Event | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States Duration: 22 10 2017 → 26 10 2017 |
Publication series
| Name | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
|---|
Conference
| Conference | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
|---|---|
| Country/Territory | United States |
| City | Savannah |
| Period | 22/10/17 → 26/10/17 |
Bibliographical note
Publisher Copyright:© 17CBMS-0001.
Keywords
- 3D Microchannel
- Hydrogel (GelMA)
- Laminar Flow
- Three-dimensional Tissue Patterning