Molecular immunobiology of macrophages: recent progress

Siamon Gordon; Sandra Clarke; David Greaves; Anthony Doyle

doi:10.1016/0952-7915(95)80025-5

Molecular immunobiology of macrophages: recent progress

Siamon Gordon^*, Sandra Clarke, David Greaves, Anthony Doyle

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

107 Scopus citations

Abstract

Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV.

Original language	English
Pages (from-to)	24-33
Number of pages	10
Journal	Current Opinion in Immunology
Volume	7
Issue number	1
DOIs	https://doi.org/10.1016/0952-7915(95)80025-5
State	Published - 02 1995
Externally published	Yes

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10.1016/0952-7915(95)80025-5

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@article{d3bc9c0ea40342019ee9296792c70fac,

title = "Molecular immunobiology of macrophages: recent progress",

abstract = "Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV.",

author = "Siamon Gordon and Sandra Clarke and David Greaves and Anthony Doyle",

year = "1995",

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doi = "10.1016/0952-7915(95)80025-5",

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AU - Clarke, Sandra

AU - Greaves, David

AU - Doyle, Anthony

PY - 1995/2

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N2 - Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV.

AB - Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV.

UR - https://www.scopus.com/pages/publications/0028905925

U2 - 10.1016/0952-7915(95)80025-5

DO - 10.1016/0952-7915(95)80025-5

M3 - 文章

C2 - 7772278

AN - SCOPUS:0028905925

SN - 0952-7915

VL - 7

SP - 24

EP - 33

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

IS - 1

ER -

Molecular immunobiology of macrophages: recent progress

Abstract

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