Mosquito larvicidal activities of extractives from black heartwood-type Cryptomeria japonica

Hui Jing Gu, Sen Sung Cheng, Chin Gi Huang, Wei June Chen, Shang Tzen Chang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

31 Scopus citations

Abstract

The purpose of this study is to determine the larvicidal activities of ethanolic extracts from leaves, wood, and bark of black heartwood-type Cryptomeria japonica against fourth-instar larvae of mosquitoes Aedes aegypti and Aedes albopictus. Among three ethanolic extracts from C. japonica, wood extract exhibited the best larvicidal activity against A. aegypti and A. albopictus with LC50 values of 63.2 and 93.8 μg/ml, respectively. Four major compounds, including ferruginol, epi-cubebol, cubebol, and isopimarol, were isolated from wood extract, and it was demonstrated that cubebol exhibited the best activity against A. aegypti and A. albopictus with LC50 values of 60.1 and 50.0 μg/ml, respectively. Our findings showed that the wood extract and cubebol from C. japonica have good potential as a source for natural larvicides.

Original languageEnglish
Pages (from-to)1455-1458
Number of pages4
JournalParasitology Research
Volume105
Issue number5
DOIs
StatePublished - 2009

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