Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection

Chia Jung Kuo; Cheng Han Lee; Ming Ling Chang; Cheng Yu Lin; Wey Ran Lin; Ming Yao Su; Cheng Hsun Chiu; Chi Nan Tseng; Yu Shan Wu; Cheng Tang Chiu; Chih Ho Lai

doi:10.1016/j.jmii.2021.03.006

Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection

Chia Jung Kuo
, Cheng Han Lee
, Ming Ling Chang
, Cheng Yu Lin
, Wey Ran Lin
, Ming Yao Su
, Cheng Hsun Chiu
, Chi Nan Tseng
, Yu Shan Wu
, Cheng Tang Chiu^*
, Chih Ho Lai^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

33 Scopus citations

Abstract

This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1% for amoxicillin, 92.7% for clarithromycin, 65.9% for metronidazole, 85.4% for levofloxacin, and 29.3% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.

Original language	English
Pages (from-to)	1184-1187
Number of pages	4
Journal	Journal of Microbiology, Immunology and Infection
Volume	54
Issue number	6
DOIs	https://doi.org/10.1016/j.jmii.2021.03.006
State	Published - 12 2021

Bibliographical note

Publisher Copyright:
© 2021

Keywords

Antimicrobial susceptibility
Refractory H. pylori
Resistance rate

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10.1016/j.jmii.2021.03.006

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title = "Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection",

abstract = "This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1\% for amoxicillin, 92.7\% for clarithromycin, 65.9\% for metronidazole, 85.4\% for levofloxacin, and 29.3\% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2\%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.",

keywords = "Antimicrobial susceptibility, Refractory H. pylori, Resistance rate",

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year = "2021",

month = dec,

doi = "10.1016/j.jmii.2021.03.006",

language = "英语",

volume = "54",

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T1 - Multidrug resistance

T2 - The clinical dilemma of refractory Helicobacter pylori infection

AU - Kuo, Chia Jung

AU - Lee, Cheng Han

AU - Chang, Ming Ling

AU - Lin, Cheng Yu

AU - Lin, Wey Ran

AU - Su, Ming Yao

AU - Chiu, Cheng Hsun

AU - Tseng, Chi Nan

AU - Wu, Yu Shan

AU - Chiu, Cheng Tang

AU - Lai, Chih Ho

PY - 2021/12

Y1 - 2021/12

N2 - This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1% for amoxicillin, 92.7% for clarithromycin, 65.9% for metronidazole, 85.4% for levofloxacin, and 29.3% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.

AB - This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1% for amoxicillin, 92.7% for clarithromycin, 65.9% for metronidazole, 85.4% for levofloxacin, and 29.3% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.

KW - Antimicrobial susceptibility

KW - Refractory H. pylori

KW - Resistance rate

UR - https://www.scopus.com/pages/publications/85103976792

U2 - 10.1016/j.jmii.2021.03.006

DO - 10.1016/j.jmii.2021.03.006

M3 - 文章

C2 - 33840604

AN - SCOPUS:85103976792

SN - 1684-1182

VL - 54

SP - 1184

EP - 1187

JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

IS - 6

ER -

Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection

Abstract

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Keywords

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