Nanoshell magnetic resonance imaging contrast agents

Chia Hao Su; Hwo Shuenn Sheu; Chia Yun Lin; Chih Chia Huang; Yi Wei Lo; Ying Chih Pu; Jun Cheng Weng; Dar Bin Shieh; Jyh Horng Chen; Chen Sheng Yeh

doi:10.1109/IMNC.2007.4456209

Nanoshell magnetic resonance imaging contrast agents

Chia Hao Su^*
, Hwo Shuenn Sheu
, Chia Yun Lin
, Chih Chia Huang
, Yi Wei Lo
, Ying Chih Pu
, Jun Cheng Weng
, Dar Bin Shieh
, Jyh Horng Chen
, Chen Sheng Yeh

^*Corresponding author for this work

Center for Micro/Nano Science and Technology
National Taiwan University
National Synchrotron Radiation Research Center Taiwan
National Cheng Kung University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

In our studies, Au₃Cu₁ hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU₃CU ₁ nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T₂-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

Original language	English
Title of host publication	Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
Pages	272-273
Number of pages	2
DOIs	https://doi.org/10.1109/IMNC.2007.4456209
State	Published - 2007
Externally published	Yes
Event	s20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan Duration: 05 11 2007 → 08 11 2007

Publication series

Name	Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC

Conference

Conference	s20th International Microprocesses and Nanotechnology Conference, MNC 2007
Country/Territory	Japan
City	Kyoto
Period	05/11/07 → 08/11/07

Access to Document

10.1109/IMNC.2007.4456209

Cite this

Su, C. H., Sheu, H. S., Lin, C. Y., Huang, C. C., Lo, Y. W., Pu, Y. C., Weng, J. C., Shieh, D. B., Chen, J. H., & Yeh, C. S. (2007). Nanoshell magnetic resonance imaging contrast agents. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC (pp. 272-273). Article 4456209 (Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC). https://doi.org/10.1109/IMNC.2007.4456209

Su, Chia Hao ; Sheu, Hwo Shuenn ; Lin, Chia Yun et al. / Nanoshell magnetic resonance imaging contrast agents. Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. pp. 272-273 (Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC).

@inproceedings{e0dcc945b0b9414d815bd5e0cf9ca2d7,

title = "Nanoshell magnetic resonance imaging contrast agents",

abstract = "In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.",

author = "Su, \{Chia Hao\} and Sheu, \{Hwo Shuenn\} and Lin, \{Chia Yun\} and Huang, \{Chih Chia\} and Lo, \{Yi Wei\} and Pu, \{Ying Chih\} and Weng, \{Jun Cheng\} and Shieh, \{Dar Bin\} and Chen, \{Jyh Horng\} and Yeh, \{Chen Sheng\}",

year = "2007",

doi = "10.1109/IMNC.2007.4456209",

language = "英语",

isbn = "4990247248",

series = "Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC",

pages = "272--273",

booktitle = "Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC",

note = "s20th International Microprocesses and Nanotechnology Conference, MNC 2007 ; Conference date: 05-11-2007 Through 08-11-2007",

}

Su, CH, Sheu, HS, Lin, CY, Huang, CC, Lo, YW, Pu, YC, Weng, JC, Shieh, DB, Chen, JH & Yeh, CS 2007, Nanoshell magnetic resonance imaging contrast agents. in Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC., 4456209, Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC, pp. 272-273, s20th International Microprocesses and Nanotechnology Conference, MNC 2007, Kyoto, Japan, 05/11/07. https://doi.org/10.1109/IMNC.2007.4456209

Nanoshell magnetic resonance imaging contrast agents. / Su, Chia Hao; Sheu, Hwo Shuenn; Lin, Chia Yun et al.
Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 272-273 4456209 (Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Nanoshell magnetic resonance imaging contrast agents

AU - Su, Chia Hao

AU - Sheu, Hwo Shuenn

AU - Lin, Chia Yun

AU - Huang, Chih Chia

AU - Lo, Yi Wei

AU - Pu, Ying Chih

AU - Weng, Jun Cheng

AU - Shieh, Dar Bin

AU - Chen, Jyh Horng

AU - Yeh, Chen Sheng

PY - 2007

Y1 - 2007

N2 - In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

AB - In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

UR - https://www.scopus.com/pages/publications/47349095397

U2 - 10.1109/IMNC.2007.4456209

DO - 10.1109/IMNC.2007.4456209

M3 - 会议稿件

AN - SCOPUS:47349095397

SN - 4990247248

SN - 9784990247249

T3 - Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC

SP - 272

EP - 273

BT - Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC

T2 - s20th International Microprocesses and Nanotechnology Conference, MNC 2007

Y2 - 5 November 2007 through 8 November 2007

ER -

Su CH, Sheu HS, Lin CY, Huang CC, Lo YW, Pu YC et al. Nanoshell magnetic resonance imaging contrast agents. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 272-273. 4456209. (Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC). doi: 10.1109/IMNC.2007.4456209

Nanoshell magnetic resonance imaging contrast agents

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