Naphthoquinone esters from the root of Rhinacanthus nasutus

Tian Shung Wu; Hua Chun Hsu; Pei Lin Wu; Yann Lii Leu; Yu Yi Chan; Ching Yuh Chern; Mou Yung Yeh; Hsien Ju Tien

doi:10.1248/cpb.46.413

Naphthoquinone esters from the root of Rhinacanthus nasutus

Tian Shung Wu^*, Hua Chun Hsu, Pei Lin Wu, Yann Lii Leu, Yu Yi Chan, Ching Yuh Chern, Mou Yung Yeh, Hsien Ju Tien

^*Corresponding author for this work

National Cheng Kung University

Research output: Contribution to journal › Journal Article › peer-review

58 Scopus citations

Abstract

Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy- 1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin- G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)- 1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.

Original language	English
Pages (from-to)	413-418
Number of pages	6
Journal	Chemical and Pharmaceutical Bulletin
Volume	46
Issue number	3
DOIs	https://doi.org/10.1248/cpb.46.413
State	Published - 1998
Externally published	Yes

Keywords

Acanthaceae
Naphthoquinone ester
Rhinacanthus nasutus

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10.1248/cpb.46.413

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title = "Naphthoquinone esters from the root of Rhinacanthus nasutus",

abstract = "Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy- 1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin- G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)- 1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.",

keywords = "Acanthaceae, Naphthoquinone ester, Rhinacanthus nasutus",

author = "Wu, {Tian Shung} and Hsu, {Hua Chun} and Wu, {Pei Lin} and Leu, {Yann Lii} and Chan, {Yu Yi} and Chern, {Ching Yuh} and Yeh, {Mou Yung} and Tien, {Hsien Ju}",

year = "1998",

doi = "10.1248/cpb.46.413",

language = "英语",

volume = "46",

pages = "413--418",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "3",

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TY - JOUR

T1 - Naphthoquinone esters from the root of Rhinacanthus nasutus

AU - Wu, Tian Shung

AU - Hsu, Hua Chun

AU - Wu, Pei Lin

AU - Leu, Yann Lii

AU - Chan, Yu Yi

AU - Chern, Ching Yuh

AU - Yeh, Mou Yung

AU - Tien, Hsien Ju

PY - 1998

Y1 - 1998

N2 - Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy- 1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin- G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)- 1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.

AB - Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy- 1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin- G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)- 1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.

KW - Acanthaceae

KW - Naphthoquinone ester

KW - Rhinacanthus nasutus

UR - http://www.scopus.com/inward/record.url?scp=0031958252&partnerID=8YFLogxK

U2 - 10.1248/cpb.46.413

DO - 10.1248/cpb.46.413

M3 - 文章

C2 - 9549882

AN - SCOPUS:0031958252

SN - 0009-2363

VL - 46

SP - 413

EP - 418

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 3

ER -

Naphthoquinone esters from the root of Rhinacanthus nasutus

Abstract

Keywords

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