TY - JOUR
T1 - Nasopharyngeal carcinoma detected by narrow-band imaging endoscopy
AU - Wang, Wen Hung
AU - Lin, Yen Chun
AU - Lee, Kam Fai
AU - Weng, Hsu Huei
PY - 2011/8
Y1 - 2011/8
N2 - The aim of the study was to investigate the novel endoscopic findings in nasopharyngeal carcinoma (NPC) under narrow-band imaging (NBI) and to determine the reliability of screening NPC by NBI. A total of 79 adults underwent nasopharyngeal biopsy. We proposed five distinctly different findings that need to be examined by NBI: Type I: brownish spots, Type II: irregular microvascular pattern (IMVP), Type III: light crests, Type IV: side-difference, Type V: presence of either IMVP or side-difference, of which last three (Type III-V) were a new concept. The results of NPC diagnosis by detecting NBI Type V pattern, the false positive, false negative, sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 6.7%, 2.9%, 97.1%, 93.3%, 91.7%, 97.7%, and 94.9%, respectively. On the other hand, there was a higher prevalence of Type I and IV patterns in T1 category NPC. The nasopharyngeal endoscopy coupled with NBI was able to provide a rapid, convenient, and highly reliable screening for high-risk populations.
AB - The aim of the study was to investigate the novel endoscopic findings in nasopharyngeal carcinoma (NPC) under narrow-band imaging (NBI) and to determine the reliability of screening NPC by NBI. A total of 79 adults underwent nasopharyngeal biopsy. We proposed five distinctly different findings that need to be examined by NBI: Type I: brownish spots, Type II: irregular microvascular pattern (IMVP), Type III: light crests, Type IV: side-difference, Type V: presence of either IMVP or side-difference, of which last three (Type III-V) were a new concept. The results of NPC diagnosis by detecting NBI Type V pattern, the false positive, false negative, sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 6.7%, 2.9%, 97.1%, 93.3%, 91.7%, 97.7%, and 94.9%, respectively. On the other hand, there was a higher prevalence of Type I and IV patterns in T1 category NPC. The nasopharyngeal endoscopy coupled with NBI was able to provide a rapid, convenient, and highly reliable screening for high-risk populations.
KW - Endoscopy
KW - Narrow-band imaging (NBI)
KW - Nasopharyngeal carcinoma (NPC)
KW - Sensitivity
KW - Specificity
UR - http://www.scopus.com/inward/record.url?scp=79960698961&partnerID=8YFLogxK
U2 - 10.1016/j.oraloncology.2011.02.012
DO - 10.1016/j.oraloncology.2011.02.012
M3 - 文章
C2 - 21393053
AN - SCOPUS:79960698961
SN - 1368-8375
VL - 47
SP - 736
EP - 741
JO - Oral Oncology
JF - Oral Oncology
IS - 8
ER -
