Abstract
Natural killer (NK) cells that provide first-line innate immune reactions against virus-infected and tumor cells have different roles in different body sites and in different stages. From the beginning of life, NK cells participate in many aspects of development, especially in a successful pregnancy and a healthy neonatal stage. This article reviews recent advances regarding the role of NK cells in implantation, placentation and immune tolerance during pregnancy as well as in the neonatal immune defense. The interactions between NK cells and other immune cells in each developmental stage are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 11-17 |
| Number of pages | 7 |
| Journal | Journal of Perinatal Medicine |
| Volume | 43 |
| Issue number | 1 |
| DOIs | |
| State | Published - 01 01 2015 |
Bibliographical note
Publisher Copyright:© 2015, Walter de Gruyter GmbH. All rights reserved.
Keywords
- Immune tolerance
- Natural killer cell
- Neonates
- Pregnancy