Neonatal natural killer cell function: Relevance to antiviral immune defense

Yen Chang Lee; Syh Jae Lin

doi:10.1155/2013/427696

Neonatal natural killer cell function: Relevance to antiviral immune defense

Yen Chang Lee, Syh Jae Lin^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Chang Gung Memorial Hospital

Research output: Contribution to journal › Review article › peer-review

34 Scopus citations

Abstract

Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

Original language	English
Article number	427696
Journal	Clinical and Developmental Immunology
Volume	2013
DOIs	https://doi.org/10.1155/2013/427696
State	Published - 2013

Access to Document

10.1155/2013/427696

Cite this

@article{db57c156883b421f9f00adf965dac53b,

title = "Neonatal natural killer cell function: Relevance to antiviral immune defense",

abstract = "Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.",

author = "Lee, {Yen Chang} and Lin, {Syh Jae}",

year = "2013",

doi = "10.1155/2013/427696",

language = "英语",

volume = "2013",

journal = "Clinical and Developmental Immunology",

issn = "1740-2522",

publisher = "Hindawi Limited",

}

TY - JOUR

T1 - Neonatal natural killer cell function

T2 - Relevance to antiviral immune defense

AU - Lee, Yen Chang

AU - Lin, Syh Jae

PY - 2013

Y1 - 2013

N2 - Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

AB - Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

UR - http://www.scopus.com/inward/record.url?scp=84884278804&partnerID=8YFLogxK

U2 - 10.1155/2013/427696

DO - 10.1155/2013/427696

M3 - 文献综述

C2 - 24066005

AN - SCOPUS:84884278804

SN - 1740-2522

VL - 2013

JO - Clinical and Developmental Immunology

JF - Clinical and Developmental Immunology

M1 - 427696

ER -

Neonatal natural killer cell function: Relevance to antiviral immune defense

Abstract

Access to Document

Other files and links

Fingerprint

Cite this