Neonatal natural killer cell function: Relevance to antiviral immune defense

Yen Chang Lee; Syh Jae Lin

doi:10.1155/2013/427696

Neonatal natural killer cell function: Relevance to antiviral immune defense

Yen Chang Lee
, Syh Jae Lin^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Chang Gung Memorial Hospital

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

Abstract

Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

Original language	English
Article number	427696
Journal	Clinical and Developmental Immunology
Volume	2013
DOIs	https://doi.org/10.1155/2013/427696
State	Published - 2013

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title = "Neonatal natural killer cell function: Relevance to antiviral immune defense",

abstract = "Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.",

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AU - Lee, Yen Chang

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AB - Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

UR - https://www.scopus.com/pages/publications/84884278804

U2 - 10.1155/2013/427696

DO - 10.1155/2013/427696

M3 - 文献综述

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AN - SCOPUS:84884278804

SN - 1740-2522

VL - 2013

JO - Clinical and Developmental Immunology

JF - Clinical and Developmental Immunology

M1 - 427696

ER -

Neonatal natural killer cell function: Relevance to antiviral immune defense

Abstract

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