Neural correlates of motor recovery after robot-assisted stroke rehabilitation: a case series study

Yang teng Fan; Keh chung Lin; Ho ling Liu; Ching yi Wu; Yau yau Wai; Tsong hai Lee

doi:10.1080/13554794.2016.1215469

Neural correlates of motor recovery after robot-assisted stroke rehabilitation: a case series study

Yang teng Fan, Keh chung Lin, Ho ling Liu, Ching yi Wu^*, Yau yau Wai, Tsong hai Lee

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

10 Scopus citations

Abstract

Robot-assisted bilateral arm therapy (RBAT) has shown promising results in stroke rehabilitation; however, connectivity mapping of the sensorimotor networks after RBAT remains unclear. We used fMRI before and after RBAT and a dose-matched control intervention (DMCI) to explore the connectivity changes in 6 subacute stroke patients. Sensorimotor functions improved in the RBAT and DMCI groups after treatment. Enhanced activation changes were observed in bilateral primary motor cortex (M1) and bilateral supplementary motor area (SMA) after RBAT. Dynamic causal model analysis revealed that interhemispheric connections were enhanced in RBAT patients. These preliminary findings suggest that intracortical and intercortical coupling might underlie poststroke RBAT.

Original language	English
Pages (from-to)	416-425
Number of pages	10
Journal	Neurocase
Volume	22
Issue number	5
DOIs	https://doi.org/10.1080/13554794.2016.1215469
State	Published - 02 09 2016

Bibliographical note

Publisher Copyright:
© 2016 Informa UK Limited, trading as Taylor & Francis Group.

Keywords

Bilateral arm training
dynamic causal model (DCM)
neuroplasticity
robot
stroke

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10.1080/13554794.2016.1215469

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title = "Neural correlates of motor recovery after robot-assisted stroke rehabilitation: a case series study",

abstract = "Robot-assisted bilateral arm therapy (RBAT) has shown promising results in stroke rehabilitation; however, connectivity mapping of the sensorimotor networks after RBAT remains unclear. We used fMRI before and after RBAT and a dose-matched control intervention (DMCI) to explore the connectivity changes in 6 subacute stroke patients. Sensorimotor functions improved in the RBAT and DMCI groups after treatment. Enhanced activation changes were observed in bilateral primary motor cortex (M1) and bilateral supplementary motor area (SMA) after RBAT. Dynamic causal model analysis revealed that interhemispheric connections were enhanced in RBAT patients. These preliminary findings suggest that intracortical and intercortical coupling might underlie poststroke RBAT.",

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doi = "10.1080/13554794.2016.1215469",

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AU - Fan, Yang teng

AU - Lin, Keh chung

AU - Liu, Ho ling

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AU - Wai, Yau yau

AU - Lee, Tsong hai

PY - 2016/9/2

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AB - Robot-assisted bilateral arm therapy (RBAT) has shown promising results in stroke rehabilitation; however, connectivity mapping of the sensorimotor networks after RBAT remains unclear. We used fMRI before and after RBAT and a dose-matched control intervention (DMCI) to explore the connectivity changes in 6 subacute stroke patients. Sensorimotor functions improved in the RBAT and DMCI groups after treatment. Enhanced activation changes were observed in bilateral primary motor cortex (M1) and bilateral supplementary motor area (SMA) after RBAT. Dynamic causal model analysis revealed that interhemispheric connections were enhanced in RBAT patients. These preliminary findings suggest that intracortical and intercortical coupling might underlie poststroke RBAT.

KW - Bilateral arm training

KW - dynamic causal model (DCM)

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Neural correlates of motor recovery after robot-assisted stroke rehabilitation: a case series study

Abstract

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Keywords

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